Haddican Madelaine, Gagliotti Matthew, Lebwohl Mark
Department of Dermatology, Mount Sinai Medical Center, New York, New York, USA.
Cutis. 2013 May;91(5):260-2.
Burning and/or stinging is one of the most common concerns expressed by patients using topical therapies for treatment of dermatologic disorders. Topical lactic acid preparations often are used to treat dry scaly skin. In this study, we compared the level of burning/stinging reported by participants with application of lactic acid cream 10% containing strontium versus ammonium lactate lotion 12% and cetearyl alcohol lotion. The mean rating of burning/stinging reported for lactic acid cream 10% with strontium and cetearyl alcohol lotion was lower than ammonium lactate lotion 12% (P<.0001). Based on the study results, lactic acid cream 10% with strontium causes less burning/stinging than ammonium lactate lotion 12%.
灼烧和/或刺痛是使用局部疗法治疗皮肤病的患者最常表达的担忧之一。局部乳酸制剂常用于治疗干性鳞屑皮肤。在本研究中，我们比较了使用含锶的10%乳酸乳膏、12%乳酸铵洗剂和鲸蜡硬脂醇洗剂的参与者报告的灼烧/刺痛程度。含锶的10%乳酸乳膏和鲸蜡硬脂醇洗剂报告的灼烧/刺痛平均评分低于12%乳酸铵洗剂（P<0.0001）。根据研究结果，含锶的10%乳酸乳膏引起的灼烧/刺痛比12%乳酸铵洗剂少。
