锶乳膏减轻化脓性汗腺炎瘙痒的疗效
Efficacy of Strontium Cream in Alleviating Pruritus in Hidradenitis Suppurativa.
作者信息
Walker Rubi, Brooks Brindley, Daveluy Steven
机构信息
Ms. Walker is with the Wayne State University School of Medicine in Detroit, Michigan.
Ms. Brooks is with HS Connect in Puyallup, Washington.
出版信息
J Clin Aesthet Dermatol. 2025 Mar;18(3):12-14.
OBJECTIVE
Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition with limited treatment options and a significant impact on quality of life. This prospective, open-label, real-world study aimed to evaluate the efficacy of strontium cream in alleviating pruritus in HS.
METHODS
Fifty participants completed baseline and one-week post-intervention surveys. Pruritus was assessed using a numeric severity scale and a qualitative survey on overall itch reduction.
RESULTS
Statistical analysis revealed a significant reduction in itching symptoms post-intervention, with mean itch scores decreasing from 3.80±0.90 at baseline to 2.28±1.50 post-intervention (<0.001). Participant feedback also indicated overall satisfaction, with 84 percent of participants willing to recommend the cream to other HS patients.
LIMITATIONS
The study relied on self-reported data, which introduces subjectivity, and the absence of a control group limits causal inference.
CONCLUSION
Strontium cream demonstrates promise as a therapeutic option for managing pruritus in HS, warranting further research.
目的
化脓性汗腺炎（HS）是一种慢性炎症性皮肤病，治疗选择有限，对生活质量有重大影响。这项前瞻性、开放标签的真实世界研究旨在评估锶乳膏缓解HS瘙痒的疗效。
方法
50名参与者完成了基线调查和干预后一周的调查。使用数字严重程度量表和关于总体瘙痒减轻情况的定性调查来评估瘙痒。
结果
统计分析显示，干预后瘙痒症状显著减轻，平均瘙痒评分从基线时的3.80±0.90降至干预后的2.28±1.50（<0.001）。参与者的反馈也表明总体满意度较高，84%的参与者愿意向其他HS患者推荐该乳膏。
局限性
该研究依赖自我报告的数据，这引入了主观性，且缺乏对照组限制了因果推断。
结论
锶乳膏有望成为治疗HS瘙痒的一种治疗选择，值得进一步研究。
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