Department of Chemistry, Northeast Normal University, Changchun 130024, PR China.
J Org Chem. 2013 Jul 19;78(14):7293-7. doi: 10.1021/jo400984h. Epub 2013 Jul 1.
Pd-catalytic C-S activation was successfully applied to initiate the cross-coupling of (2-methylthio-3-ester)benzofurans with 2-hydroxyphenylboronic acids and sequential intramolecular transesterification process under Liebeskind-Srogl conditions. Thus, a novel [3 + 3] annulation strategy for efficient synthesis of coumestan derivatives has been developed from readily available starting materials.
钯催化的 C-S 活化成功地引发了（2-甲基硫代-3-酯基）苯并呋喃与 2-羟基苯硼酸的交叉偶联反应，并在 Liebeskind-Srogl 条件下进行了连续的分子内酯交换过程。因此，从易得的起始原料出发，开发了一种用于高效合成香豆素衍生物的新型[3+3]环合策略。
