Altering the course of type 1 diabetes: an update on prevention and new-onset clinical trials.
作者信息
Thomas Hilary R, Gitelman Stephen E
机构信息
Department of Medicine and Diabetes Center, University of California, San Francisco, CA 94143, USA.
出版信息
Pediatr Diabetes. 2013 Aug;14(5):311-21. doi: 10.1111/pedi.12040. Epub 2013 Jun 17.
Abstract
摘要
相似文献
1
Altering the course of type 1 diabetes: an update on prevention and new-onset clinical trials.改变1型糖尿病的病程：预防及新发病例临床试验的最新进展
Pediatr Diabetes. 2013 Aug;14(5):311-21. doi: 10.1111/pedi.12040. Epub 2013 Jun 17.
2
Immunotherapy of type 1 diabetes.1型糖尿病的免疫疗法。
Arch Immunol Ther Exp (Warsz). 2008 Jul-Aug;56(4):227-36. doi: 10.1007/s00005-008-0025-2. Epub 2008 Jul 29.
3
Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials.近期从预防和新发1型糖尿病免疫治疗试验中吸取的经验教训。
Diabetes. 2013 Jan;62(1):9-17. doi: 10.2337/db12-0562.
4
T cells in type 1 diabetes: Instructors, regulators and effectors: A comprehensive review.1 型糖尿病中的 T 细胞：指导者、调节剂和效应器：全面综述。
J Autoimmun. 2016 Jan;66:7-16. doi: 10.1016/j.jaut.2015.08.012. Epub 2015 Sep 3.
5
Current and past prevention and intervention trials in type 1 diabetes.1型糖尿病当前及既往的预防与干预试验。
Novartis Found Symp. 2008;292:99-109; discussion 109-12, 122-9, 202-3. doi: 10.1002/9780470697405.ch8.
6
Towards a curative therapy in type 1 diabetes: remission of autoimmunity, maintenance and augmentation of beta cell mass.迈向1型糖尿病的治愈性疗法：自身免疫的缓解、β细胞质量的维持与增加。
Novartis Found Symp. 2008;292:146-55; discussion 155-8, 202-3. doi: 10.1002/9780470697405.ch14.
7
Efforts to prevent and halt autoimmune beta cell destruction.努力预防和阻止自身免疫性β细胞破坏。
Endocrinol Metab Clin North Am. 2010 Sep;39(3):527-39. doi: 10.1016/j.ecl.2010.05.006.
8
New Insights into Immunotherapy Strategies for Treating Autoimmune Diabetes.免疫疗法治疗自身免疫性糖尿病的新见解。
Int J Mol Sci. 2019 Sep 26;20(19):4789. doi: 10.3390/ijms20194789.
9
Reestablishing T Cell Tolerance by Antibody-Based Therapy in Type 1 Diabetes.通过基于抗体的疗法在1型糖尿病中重建T细胞耐受性。
Arch Immunol Ther Exp (Warsz). 2015 Aug;63(4):239-50. doi: 10.1007/s00005-015-0336-z. Epub 2015 Mar 20.
10
Prevention versus intervention of type 1 diabetes.1 型糖尿病的预防与干预。
Clin Immunol. 2013 Dec;149(3):332-8. doi: 10.1016/j.clim.2013.05.018. Epub 2013 Jun 10.
引用本文的文献
1
Inverse Vaccination for Autoimmune Diseases: Insights into the Role of B Lymphocytes.自身免疫性疾病的反向疫苗接种：对B淋巴细胞作用的见解
Cells. 2025 Jul 16;14(14):1085. doi: 10.3390/cells14141085.
2
A novel platform for isotype-specific testing of autoantibodies.一种用于自身抗体同种型特异性检测的新型平台。
PLoS One. 2019 Feb 7;14(2):e0211596. doi: 10.1371/journal.pone.0211596. eCollection 2019.
3
Gene Therapy-Induced Antigen-Specific Tregs Inhibit Neuro-inflammation and Reverse Disease in a Mouse Model of Multiple Sclerosis.基因治疗诱导的抗原特异性调节性 T 细胞抑制神经炎症并逆转多发性硬化症小鼠模型的疾病。
Mol Ther. 2018 Jan 3;26(1):173-183. doi: 10.1016/j.ymthe.2017.09.001. Epub 2017 Sep 21.
4
New directions for rabbit antithymocyte globulin (Thymoglobulin(®)) in solid organ transplants, stem cell transplants and autoimmunity.兔抗胸腺细胞球蛋白（即复宁®）在实体器官移植、干细胞移植和自身免疫性疾病中的新应用方向
Drugs. 2014 Sep;74(14):1605-34. doi: 10.1007/s40265-014-0277-6.
5
Combination therapy with sitagliptin and lansoprazole in patients with recent-onset type 1 diabetes (REPAIR-T1D): 12-month results of a multicentre, randomised, placebo-controlled, phase 2 trial.在近期发病的 1 型糖尿病患者中应用西他列汀联合兰索拉唑治疗（REPAIR-T1D）：一项多中心、随机、安慰剂对照、2 期临床试验的 12 个月结果。
Lancet Diabetes Endocrinol. 2014 Sep;2(9):710-8. doi: 10.1016/S2213-8587(14)70115-9. Epub 2014 Jul 2.
本文引用的文献
1
Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials.近期发病 1 型糖尿病的白细胞介素-1拮抗作用：两项多中心、随机、双盲、安慰剂对照试验。
Lancet. 2013 Jun 1;381(9881):1905-15. doi: 10.1016/S0140-6736(13)60023-9. Epub 2013 Apr 5.
2
Teplizumab treatment may improve C-peptide responses in participants with type 1 diabetes after the new-onset period: a randomised controlled trial.特立帕肽治疗可能改善新诊断的 1 型糖尿病患者的 C 肽反应：一项随机对照试验。
Diabetologia. 2013 Feb;56(2):391-400. doi: 10.1007/s00125-012-2753-4. Epub 2012 Oct 21.
3
Administration of CD4+CD25highCD127- regulatory T cells preserves β-cell function in type 1 diabetes in children.CD4+CD25highCD127-调节性 T 细胞的输注可维持儿童 1 型糖尿病的胰岛β细胞功能。
Diabetes Care. 2012 Sep;35(9):1817-20. doi: 10.2337/dc12-0038. Epub 2012 Jun 20.
4
Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function.雷帕霉素/白细胞介素 2 联合疗法在 1 型糖尿病患者中增强 Tregs 但短暂损害β细胞功能。
Diabetes. 2012 Sep;61(9):2340-8. doi: 10.2337/db12-0049. Epub 2012 Jun 20.
5
Breakdown in peripheral tolerance in type 1 diabetes in mice and humans.1 型糖尿病小鼠和人类外周耐受的破坏。
Cold Spring Harb Perspect Med. 2012 Mar;2(3):a007807. doi: 10.1101/cshperspect.a007807.
6
GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus.GAD65 抗原治疗新诊断的 1 型糖尿病。
N Engl J Med. 2012 Feb 2;366(5):433-42. doi: 10.1056/NEJMoa1107096.
7
Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis.调节性 T 细胞对 HCV 诱导血管炎的低剂量白细胞介素-2 的反应。
N Engl J Med. 2011 Dec 1;365(22):2067-77. doi: 10.1056/NEJMoa1105143.
8
Interleukin-2 and regulatory T cells in graft-versus-host disease.白细胞介素 2 与移植物抗宿主病中的调节性 T 细胞。
N Engl J Med. 2011 Dec 1;365(22):2055-66. doi: 10.1056/NEJMoa1108188.
9
Maternal serum levels of 25-hydroxy-vitamin D during pregnancy and risk of type 1 diabetes in the offspring.孕妇血清 25-羟维生素 D 水平与子代 1 型糖尿病风险的关系。
Diabetes. 2012 Jan;61(1):175-8. doi: 10.2337/db11-0875. Epub 2011 Nov 28.
10
Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide.自体脐带血输注治疗 1 型糖尿病患儿未能保留 C 肽。
Diabetes Care. 2011 Dec;34(12):2567-9. doi: 10.2337/dc11-1406. Epub 2011 Oct 19.
Zotero 插件