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根据 ICNIRP 2010 指南,皮肤电导率在低频暴露评估外周神经组织中的作用。

The role of skin conductivity in a low frequency exposure assessment for peripheral nerve tissue according to the ICNIRP 2010 guidelines.

机构信息

Seibersdorf Laboratories, EMC & Optics, A-2444 Seibersdorf, Austria.

出版信息

Phys Med Biol. 2013 Jul 7;58(13):4703-16. doi: 10.1088/0031-9155/58/13/4703. Epub 2013 Jun 18.

Abstract

Based on numerical computations using commercially available finite difference time domain code and a state-of-the art anatomical model of a 5-year old child, the influence of skin conductivity on the induced electric field strength inside the tissue for homogeneous front-to-back magnetic field exposure and homogeneous vertical electric field exposure was computed. Both ungrounded as well as grounded conditions of the body model were considered. For electric field strengths induced inside CNS tissue the impact of skin conductivity was found to be less than 15%. However, the results demonstrated that the use of skin conductivity values as obtainable from the most widely used data base of dielectric tissue properties and recommended by safety standards are not suitable for exposure assessment with respect to peripheral nerve tissue according to the ICNIRP 2010 guidelines in which the use of the induced electric field strengths inside the skin is suggested as a conservative surrogate for peripheral nerve exposure. This is due to the fact that the skin conductivity values derived from these data bases refer to the stratum corneum, the uppermost layer of the skin, which does not contain any nerve or receptor cells to be protected from stimulation effects. Using these skin conductivity values which are approximately a factor 250-500 lower than skin conductivity values used in studies on which the ICNIRP 2010 guidelines are based on, may lead to overestimations of the induced electric field strengths inside the skin by substantially more than a factor of 10. However, reliable conductivity data of deeper skin layers where nerve and preceptor cells are located is very limited. It is therefore recommended to include appropriate background information in the ICNIRP guidelines and the dielectric tissue property databases, and to put some emphasis on a detailed layer-specific characterization of skin conductivity in near future.

摘要

基于使用商业可用的有限差分时域代码和最先进的 5 岁儿童解剖模型的数值计算,计算了皮肤电导率对组织内感应电场强度的影响,用于均匀前后磁场暴露和均匀垂直电场暴露。考虑了身体模型的未接地和接地条件。对于 CNS 组织内感应的电场强度,皮肤电导率的影响小于 15%。然而,结果表明,根据 ICNIRP 2010 指南,使用最广泛的介电组织特性数据库中可获得的皮肤电导率值以及安全标准推荐的值,不适合进行外周神经组织的暴露评估,根据该指南,建议使用皮肤内感应电场强度作为外周神经暴露的保守替代物。这是因为这些数据库中得出的皮肤电导率值是指皮肤的最上层表皮层,其中不包含任何需要免受刺激影响的神经或受体细胞。使用这些皮肤电导率值,其值大约比基于 ICNIRP 2010 指南的研究中使用的皮肤电导率值低 250-500 倍,可能会导致皮肤内感应电场强度的高估超过 10 倍。然而,有关神经和受体细胞所在的深层皮肤层的可靠电导率数据非常有限。因此,建议在 ICNIRP 指南和介电组织特性数据库中包含适当的背景信息,并在不久的将来强调对皮肤电导率进行详细的特定于层的特性描述。

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