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成体干细胞与心脏再生。

Adult stem cells and cardiac regeneration.

机构信息

Regenerative Medicine Program, Sprott Centre for Stem Cell Research, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada,

出版信息

Stem Cell Rev Rep. 2013 Oct;9(5):537-40. doi: 10.1007/s12015-013-9448-1.

Abstract

There is worldwide demand for therapies to promote the robust repair and regeneration with maximum regain of function of particular tissues and organs damaged by disease or injury. The potential role of adult stem cells has been highlighted by an increasing number of in vitro and in vivo studies. Nowhere is this more evident than in adult stem cell-based therapies being explored to promote cardiac regeneration. In spite of encouraging advances, significant challenges remain.

摘要

全世界都需要治疗方法,以促进特定组织和器官的强大修复和再生,使因疾病或损伤而受损的功能得到最大程度的恢复。越来越多的体外和体内研究突出了成人干细胞的潜在作用。在基于成人干细胞的治疗方法中,这一点在促进心脏再生方面表现得最为明显。尽管取得了令人鼓舞的进展,但仍存在重大挑战。

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