Khorvash Fariborz, Rahimi Marzieh, Bagherian-Sararoudi Reza, Mousavi Sayed Ali, Ebneshahidi Alireza, Amirpour Afshin, Mirabdollahi Mansoureh Alsadat
Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Int J Prev Med. 2013 May;4(Suppl 2):S250-5.
In some studies, the involvement of dangerous psychological and behavioral factors in etiology and physiotherapy of vascular disturbances have been shown. In other studies, the relationship between the personality type and increase in cardiovascular disease has been demonstrated. The type D personality is defined as having two characteristics of negative affect and social inhibition. It is thought that individuals with type D personality are at increased risk of carotid artery intima-media thickening which predisposes them to vascular disease that is one of the most important factors for the stroke. In this study, we try to determine whether type D personality is a contributing factor to an increase in the intima-media of the carotid artery. This study was done in 2012 in the teaching hospital of Alzahra in Isfahan Iran.
This is a case/control study which is done at Alzahra hospital in Isfahan in 2011-12. The statistical population in this study is composed of individuals who do not have any risk factors for stroke and are randomly selected among the hospital staff or the patient's family members who accompanied the patient at the hospital. They filled out a questioner that would assist in detecting type D personality. A carotid Doppler ultrasound that measures the intima-media thickness in the selected individuals was performed. The information obtained from the study was evaluated by Statistical Product and Service Solutions (SPSS) software and the intima-media thicknesses were compared in two groups of patients.
The average thickness of intima media in two groups, consist of placebo and patients, was 0.739 ± 0.12 and 0.759 ± 0.14 millimeter, respectively. There was no meaningful difference between the two groups based on t-test values (P = 0.19). It is important to note that based on the results, 22.9% of placebos and 48.6% of individuals with type D personality presented with abnormal thickness. The difference between the two groups were meaningful based on Chi-Squared test (P = 0.001).
We conclude that type D personality increases the risk of cardiovascular diseases specially the stroke and myocardial infarction due to the higher prevalence of hormonal imbalances leading to arterial vasospasm and atherosclerotic disease. As a result, it is necessary to evaluate and treat these patients due to increased risk of atherosclerotic diseases, stoke, and myocardial infarction.
在一些研究中，已表明危险的心理和行为因素参与血管紊乱的病因学和物理治疗。在其他研究中，已证实人格类型与心血管疾病增加之间的关系。D型人格被定义为具有消极情感和社交抑制这两个特征。据认为，D型人格的个体颈动脉内膜中层增厚的风险增加，这使他们易患血管疾病，而血管疾病是中风最重要的因素之一。在本研究中，我们试图确定D型人格是否是颈动脉内膜中层增厚增加的一个促成因素。本研究于2012年在伊朗伊斯法罕的阿尔扎赫拉教学医院进行。
这是一项于2011 - 2012年在伊斯法罕的阿尔扎赫拉医院进行的病例/对照研究。本研究的统计人群由没有任何中风危险因素的个体组成，这些个体是从医院工作人员或在医院陪伴患者的患者家属中随机选取的。他们填写了一份有助于检测D型人格的问卷。对选定个体进行了测量内膜中层厚度的颈动脉多普勒超声检查。从研究中获得的信息通过统计产品与服务解决方案（SPSS）软件进行评估，并对两组患者的内膜中层厚度进行比较。
安慰剂组和患者组两组内膜中层的平均厚度分别为0.739±0.12毫米和0.759±0.14毫米。根据t检验值，两组之间没有显著差异（P = 0.19）。需要注意的是，根据结果，22.9%的安慰剂组个体和48.6%的D型人格个体存在异常厚度。基于卡方检验（P = 0.001），两组之间的差异具有显著性。
我们得出结论，D型人格会增加心血管疾病的风险，特别是中风和心肌梗死，因为激素失衡导致动脉血管痉挛和动脉粥样硬化疾病更为普遍。因此，由于动脉粥样硬化疾病、中风和心肌梗死的风险增加，有必要对这些患者进行评估和治疗。
