严重非结合性高胆红素血症：1加1等于3？
Severe unconjugated hyperbilirubinaemia: one and one makes three?
作者信息
Naha Kushal, Dasari Sowjanya, Vivek G, Hande Manjunath, Acharya Vasudev
机构信息
Department of Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
出版信息
BMJ Case Rep. 2013 Jun 18;2013:bcr2013009962. doi: 10.1136/bcr-2013-009962.
Abstract
A 38-year-old housewife presented with a 3-month history of gradually progressive fatigue and deepening jaundice as well as a history of mild fluctuating jaundice since childhood. General examination revealed an obvious icterus. Systemic examination was normal. Laboratory tests confirmed unconjugated hyperbilirubinaemia. Further evaluation yielded a diagnosis of vitamin B12 deficiency on a background of Gilbert's syndrome.
摘要
一名38岁的家庭主妇，有3个月逐渐加重的疲劳和黄疸加深病史，且自童年起就有轻度波动性黄疸病史。全身检查发现明显黄疸。系统检查正常。实验室检查证实为非结合性高胆红素血症。进一步评估诊断为吉尔伯特综合征背景下的维生素B12缺乏症。
相似文献
1
Severe unconjugated hyperbilirubinaemia: one and one makes three?严重非结合性高胆红素血症：1加1等于3？
BMJ Case Rep. 2013 Jun 18;2013:bcr2013009962. doi: 10.1136/bcr-2013-009962.
2
[Gilbert's syndrome in children--our experience].[儿童吉尔伯特综合征——我们的经验]
Srp Arh Celok Lek. 2007 May-Jun;135(5-6):317-20. doi: 10.2298/sarh0706317r.
3
Hereditary spherocytosis coexisting with Gilbert's syndrome: a diagnostic dilemma.遗传性球形红细胞增多症与吉尔伯特综合征并存：诊断难题。
Singapore Med J. 2008 Nov;49(11):e308-9.
4
Two easy-to-perform diagnostic tests for Gilbert's syndrome.两种易于实施的吉尔伯特综合征诊断测试。
Zhonghua Yi Xue Za Zhi (Taipei). 2002 May;65(5):231-4.
5
The nicotinic acid provocation test and unconjugated hyperbilirubinaemia.烟酸激发试验与非结合性高胆红素血症
Ulster Med J. 1991 Apr;60(1):49-52.
6
Intractable neonatal jaundice due to hereditary spherocytosis and Gilbert's syndrome.遗传性球形红细胞增多症和吉尔伯特综合征所致的难治性新生儿黄疸。
BMJ Case Rep. 2011 Jul 28;2011:bcr0520114293. doi: 10.1136/bcr.05.2011.4293.
7
8
Diagnosis of Gilbert's syndrome. Reliability of the caloric restriction and phenobarbital stimulation tests.吉尔伯特综合征的诊断。热量限制和苯巴比妥刺激试验的可靠性。
Scand J Gastroenterol. 1981;16(5):699-703. doi: 10.3109/00365528109182033.
9
Tuberculous lymphadenitis and borderline leprosy in a patient with isolated unconjugated hyperbilirubinaemia.一名患有单纯非结合性高胆红素血症的患者出现结核性淋巴结炎和界线类麻风。
BMJ Case Rep. 2014 Nov 9;2014:bcr2014205311. doi: 10.1136/bcr-2014-205311.
10
Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome.胆红素UDP-葡萄糖醛酸基转移酶基因启动子的遗传变异与吉尔伯特综合征
Lancet. 1996 Mar 2;347(9001):578-81. doi: 10.1016/s0140-6736(96)91273-8.
引用本文的文献
1
Occurrence of Recurrent Aphthous Stomatitis (RAS) as a Rare Oral Manifestation in a Patient with Gilbert's Syndrome.复发性阿弗他口炎（RAS）作为吉尔伯特综合征患者罕见的口腔表现出现。
Case Rep Dent. 2021 Apr 16;2021:6648729. doi: 10.1155/2021/6648729. eCollection 2021.
本文引用的文献
1
An unusual cause for recurrent jaundice in an otherwise healthy male.一名原本健康男性反复出现黄疸的不寻常病因。
Australas Med J. 2012;5(10):541-3. doi: 10.4066/AMJ.2012.1404. Epub 2012 Oct 31.
2
Gilbert syndrome increasing unconjugated hyperbilirubinemia in a child with hereditary spherocytosis.吉尔伯特综合征加重了一名遗传性球形红细胞增多症患儿的非结合性高胆红素血症。
J Pediatr Hematol Oncol. 2012 Jan;34(1):54-6. doi: 10.1097/MPH.0b013e318228fdd1.
3
A case of concomitant Gilbert's syndrome and hereditary spherocytosis.一例吉尔伯特综合征合并遗传性球形红细胞增多症。
Korean J Hepatol. 2010 Sep;16(3):321-4. doi: 10.3350/kjhep.2010.16.3.321.
4
Hereditary spherocytosis coexisting with Gilbert's syndrome: a diagnostic dilemma.遗传性球形红细胞增多症与吉尔伯特综合征并存：诊断难题。
Singapore Med J. 2008 Nov;49(11):e308-9.
5
Severe hyperbilirubinemia in a 10-year-old girl with a combined disorder of hereditary spherocytosis and Gilbert syndrome.一名患有遗传性球形红细胞增多症和吉尔伯特综合征合并症的10岁女孩出现严重高胆红素血症。
Pediatr Int. 2007 Aug;49(4):540-2. doi: 10.1111/j.1442-200X.2007.02410.x.
6
Megaloblastic anemia and other causes of macrocytosis.巨幼细胞贫血及其他大细胞性贫血的病因。
Clin Med Res. 2006 Sep;4(3):236-41. doi: 10.3121/cmr.4.3.236.
7
Concomitant Gilbert's syndrome and thalassemia trait.伴有吉尔伯特综合征和地中海贫血特质。
J Assoc Physicians India. 2003 Mar;51:316-7.
8
Severe jaundice in a patient with a previously undescribed glucose-6-phosphate dehydrogenase (G6PD) mutation and Gilbert syndrome.一名患有先前未描述的葡萄糖-6-磷酸脱氢酶（G6PD）突变和吉尔伯特综合征的患者出现严重黄疸。
Blood Cells Mol Dis. 2002 Mar-Apr;28(2):104-7. doi: 10.1006/bcmd.2002.0491.
9
Molecular diagnosis of a familial nonhemolytic hyperbilirubinemia (Gilbert's syndrome) in healthy subjects.健康受试者家族性非溶血性高胆红素血症（吉尔伯特综合征）的分子诊断
Hepatology. 2000 Oct;32(4 Pt 1):792-5. doi: 10.1053/jhep.2000.18193.
10
The reciprocal relation between caloric intake and the degree of hyperbilirubinemia in Gilbert's syndrome.吉尔伯特综合征中热量摄入与高胆红素血症程度之间的相互关系。
N Engl J Med. 1970 Jul 23;283(4):170-2. doi: 10.1056/NEJM197007232830403.
Zotero 插件