Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Kiinamyllynkatu 10, 20520, Turku, Finland,
Int J Behav Med. 2014 Jun;21(3):464-9. doi: 10.1007/s12529-013-9327-9.
Job strain has been associated with depressive symptoms, and depression has been associated with low bone mineral density (BMD).
The associations between BMD and job strain have not been studied. We examined the relations between BMD, job strain, and depressive symptoms in a population-based group of young adults in Finland.
Ultrasonic measurement of BMD at the calcaneus was performed on 777 participants (men 45 %, aged 30-45) drawn from the Cardiovascular Risk in Young Finns Study. Job strain was assessed by self-administered questionnaires by the combination of job demands and job control. Depressive symptoms were assessed with a modified Beck Depression Inventory. The effects of job strain on BMD were studied with multivariable analyses with age, sex, BMI, vitamin D, and calcium intake, physical activity, cigarette smoking, alcohol use, and depressive symptoms as covariates.
Depressive symptoms were independently associated with lower BMD T score in participants with high job strain (β = -0.241, p = 0.02), but depressive symptoms were not significantly associated with BMD in the low (β = -0.160, p = 0.26) and intermediate (β = -0.042, p = 0.66) job strain categories.
The results suggest that job strain modifies the association between depressive symptoms and BMD. Depressed individuals with high work-related stress might be in increased risk of lower bone mineral density.
工作压力与抑郁症状有关，而抑郁与低骨密度（BMD）有关。
尚未研究 BMD 与工作压力之间的关系。我们在芬兰的一项基于人群的年轻成年人研究中，检查了 BMD、工作压力和抑郁症状之间的关系。
对来自心血管风险在年轻芬兰人中的 777 名参与者（男性 45%，年龄 30-45 岁）进行了跟骨超声测量。通过自我管理的问卷评估了工作压力，通过工作需求和工作控制的组合来评估工作压力。使用改良贝克抑郁量表评估抑郁症状。使用多变量分析，将年龄、性别、BMI、维生素 D 和钙摄入量、体力活动、吸烟、饮酒和抑郁症状作为协变量，研究了工作压力对 BMD 的影响。
在高工作压力的参与者中，抑郁症状与较低的 BMD T 评分独立相关（β=-0.241，p=0.02），但在低（β=-0.160，p=0.26）和中等（β=-0.042，p=0.66）工作压力类别中，抑郁症状与 BMD 无显著相关性。
结果表明，工作压力改变了抑郁症状与 BMD 之间的关联。工作压力大的抑郁个体可能面临较低骨密度的风险增加。
