Shakirova E M, Pereverzeva O G
Vopr Pitan. 1990 Mar-Apr(2):37-41.
The content of 25-hydroxycholecalciferol, calcium and phosphorus in blood serum was measured in 80 premature infants aged 12 to 120 days depending on the type of feeding and rickets prevention. Administration of vitamin D in a dose of 400 IU and increase of calcium consumption up to 110-120 mg and of phosphorus to 45-57 mg per kg body weight at the expense of calcinated cottage introduction into the diet provide for the optimal levels of 25-hydroxycholecalciferol and calcium in the blood of these children. Administration of calcium and phosphorus to children receiving breast feeding in doses of 80-90 and 33-37 mg/kg, respectively, is not sufficient for the maintenance of calcium homeostasis and endogenous supply with vitamin D even if the latter is given prophylactically. When children are fed with the mixture Maliutka, the maximal permissible dose of vitamin D may amount to 800 IU a day. Administration of vitamin D in a dose of 3750 IU is fraught with a danger of hypervitaminosis D in the presence of high alimentary supply with calcium and phosphorus and does not make calcium homeostasis return to normal in the presence of low supply with these mineral substances.
根据喂养方式和佝偻病预防措施，对80名12至120日龄的早产儿血清中25-羟基胆钙化醇、钙和磷的含量进行了测定。通过在饮食中引入钙化酪乳，将维生素D的剂量增加至400 IU，并将钙的摄入量提高至每公斤体重110 - 120毫克，磷的摄入量提高至45 - 57毫克，可使这些儿童血液中25-羟基胆钙化醇和钙达到最佳水平。对于接受母乳喂养的儿童，分别给予80 - 90毫克/千克和33 - 37毫克/千克的钙和磷，即使预防性给予维生素D，也不足以维持钙稳态和内源性维生素D供应。当儿童食用“Maliutka”配方奶时，维生素D的最大允许剂量可达每天800 IU。在钙和磷摄入量高的情况下，给予3750 IU的维生素D有维生素D过量的风险，而在这些矿物质摄入量低的情况下，也不能使钙稳态恢复正常。
