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[不同喂养方式下早产儿的维生素D摄入量及其磷钙代谢状况与佝偻病预防]

[The vitamin D allowance of premature infants and their phosphorus-calcium metabolic status with different types of feeding and rickets prevention].

作者信息

Shakirova E M, Pereverzeva O G

出版信息

Vopr Pitan. 1990 Mar-Apr(2):37-41.

PMID:2378101
Abstract

The content of 25-hydroxycholecalciferol, calcium and phosphorus in blood serum was measured in 80 premature infants aged 12 to 120 days depending on the type of feeding and rickets prevention. Administration of vitamin D in a dose of 400 IU and increase of calcium consumption up to 110-120 mg and of phosphorus to 45-57 mg per kg body weight at the expense of calcinated cottage introduction into the diet provide for the optimal levels of 25-hydroxycholecalciferol and calcium in the blood of these children. Administration of calcium and phosphorus to children receiving breast feeding in doses of 80-90 and 33-37 mg/kg, respectively, is not sufficient for the maintenance of calcium homeostasis and endogenous supply with vitamin D even if the latter is given prophylactically. When children are fed with the mixture Maliutka, the maximal permissible dose of vitamin D may amount to 800 IU a day. Administration of vitamin D in a dose of 3750 IU is fraught with a danger of hypervitaminosis D in the presence of high alimentary supply with calcium and phosphorus and does not make calcium homeostasis return to normal in the presence of low supply with these mineral substances.

摘要

根据喂养方式和佝偻病预防措施,对80名12至120日龄的早产儿血清中25-羟基胆钙化醇、钙和磷的含量进行了测定。通过在饮食中引入钙化酪乳,将维生素D的剂量增加至400 IU,并将钙的摄入量提高至每公斤体重110 - 120毫克,磷的摄入量提高至45 - 57毫克,可使这些儿童血液中25-羟基胆钙化醇和钙达到最佳水平。对于接受母乳喂养的儿童,分别给予80 - 90毫克/千克和33 - 37毫克/千克的钙和磷,即使预防性给予维生素D,也不足以维持钙稳态和内源性维生素D供应。当儿童食用“Maliutka”配方奶时,维生素D的最大允许剂量可达每天800 IU。在钙和磷摄入量高的情况下,给予3750 IU的维生素D有维生素D过量的风险,而在这些矿物质摄入量低的情况下,也不能使钙稳态恢复正常。

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