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[关于维生素D、钙和磷需求的当前观点,特别是在配方奶喂养婴儿中]

[Current views on requirements for vitamin D, calcium and phosphorus, particularly in formula fed infants].

作者信息

Ksiazyk J

机构信息

Klinika Pediatrii, Instytut Matki i Dziecka, Kasprzaka 17a, 01-211, Warszawa, Poland.

出版信息

Med Wieku Rozwoj. 2000 Oct-Dec;4(4):423-30.

Abstract

Calcium (Ca) and phosphorus (P) absorption depends on vitamin D. Vitamin deficiency in children results in rickets and osteoporosis in adults. Prematurely born infants are at risk of osteopenia and rickets. Skin synthesis of vitamin D can obtain the level of 10 000 IU (250 ug) when the whole body is exposed to the sun. Recent opinion on vitamin D requirement establishes the level of more than 80 nmol/L of 25(OH)D. There are no recommendations for children but it seems that due to the risk of skin cancer, exposure to the sun in children will be limited and as a result higher dose of vitamin D will be needed. Calcium and phosphorus are the most common minerals of the human body. Calcium concentration in human milk is not related to the intake. Calcium intake of calcium in premature infants is 70-140 mg/100 kcal. Phosphorus content in breast milk, even as low as 15 mg%, can maintain the optimal Ca/P ratio of 2/1. Prolonged breast feeding without additional Ca and P, may result in reduced bone mineralisation. Higher content of calcium in infant formula in comparison to human milk is due to the fact that Ca absorption from breast milk is 60% in comparison to 40% absorption from the formula.

摘要

钙(Ca)和磷(P)的吸收依赖于维生素D。儿童维生素缺乏会导致佝偻病,成人则会引发骨质疏松症。早产儿有患骨质减少和佝偻病的风险。当全身暴露于阳光下时,皮肤合成的维生素D水平可达10000国际单位(250微克)。近期关于维生素D需求量的观点认为,25(OH)D的水平应超过80纳摩尔/升。目前尚无针对儿童的相关建议,但由于存在皮肤癌风险,儿童晒太阳的机会可能会受到限制,因此可能需要更高剂量的维生素D。钙和磷是人体最常见的矿物质。人乳中的钙浓度与摄入量无关。早产儿的钙摄入量为70 - 140毫克/100千卡。母乳中的磷含量即使低至15毫克%,也能维持2/1的最佳钙磷比。长时间纯母乳喂养而不额外补充钙和磷,可能会导致骨矿化减少。与母乳相比,婴儿配方奶粉中钙含量更高,这是因为母乳中钙的吸收率为60%,而配方奶粉中钙的吸收率为40%。

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