一项关于有和没有关节活动受限（LJM）的胰岛素依赖型糖尿病患者呼吸功能的研究。

A study of the respiratory function in insulin-dependent diabetic patients with and without limited joint mobility (LJM).

作者信息

Vera M, Suffos R, Carriles M, Güell R, Picasso N, Alvarez M C

机构信息

Instituto Nacional de Endocrinología, Habana, Cuba.

出版信息

Acta Diabetol Lat. 1990 Apr-Jun;27(2):113-7. doi: 10.1007/BF02581283.

DOI:10.1007/BF02581283

PMID:2378196

Abstract

The respiratory function of 51 insulin-dependent diabetic patients (31 with and 20 without LJM) was studied. The variables age, diabetes duration, height, and metabolic control were similar for both groups. Vital capacity (VC), forced expiratory volume (FEV), mean maximum expiratory flow (MMEF), and FEV/VC ratio were determined before and after the administration of a bronchodilator. VC, FEV, and MMEF showed significantly lower values (p less than 0.02) in patients without LJM as compared to those with LJM. It is suggested that these alterations may be due to abnormalities of collagen fibers and elasticity in the lung and are not related to reversible bronchial obstruction. We believe that LJM is an extrinsic manifestation of a systemic process, aggravating the prognosis of diabetes mellitus.

摘要

对51例胰岛素依赖型糖尿病患者（31例有肺功能减退（LJM），20例无LJM）的呼吸功能进行了研究。两组患者的年龄、糖尿病病程、身高和代谢控制情况相似。在给予支气管扩张剂前后测定肺活量（VC）、用力呼气量（FEV）、平均最大呼气流量（MMEF）和FEV/VC比值。与有LJM的患者相比，无LJM的患者的VC、FEV和MMEF值显著更低（p<0.02）。提示这些改变可能是由于肺内胶原纤维和弹性异常所致，与可逆性支气管阻塞无关。我们认为LJM是一种全身过程的外在表现，会加重糖尿病的预后。