Clarke C F, Piesowicz A T, Spathis G S
Queen Mary's Hospital for Children, Carshalton, Surrey.
Ann Rheum Dis. 1990 Apr;49(4):236-7. doi: 10.1136/ard.49.4.236.
Joint mobility was studied in 70 children with insulin dependent diabetes mellitus aged 8-17 years, and the prevalence of limited joint mobility (LJM) was found to be 31% (22/70). This figure fell to only 7% (5/70) when an alternative method of assessment was used. A high number of non-diabetic, non-sibling controls (6/51 (12%] were found to have LJM. There was a trend towards an increasing prevalence of LJM with increasing age and duration of diabetes, but it was also found in patients with recent onset diabetes. A large proportion of prepubertal patients were noted to have LJM. No correlation was found between LJM and either short stature or diabetic control. There is a need for standardisation of the methods used to define and stage LJM in diabetic patients, and the significance of this clinical finding remains unclear.
对70名年龄在8至17岁的胰岛素依赖型糖尿病儿童的关节活动度进行了研究,发现关节活动受限(LJM)的患病率为31%(22/70)。当使用另一种评估方法时,这一数字降至仅7%(5/70)。大量非糖尿病、非同胞对照者(6/51(12%))被发现存在LJM。随着年龄增长和糖尿病病程延长,LJM的患病率有上升趋势,但在近期发病的糖尿病患者中也有发现。注意到很大一部分青春期前患者存在LJM。未发现LJM与身材矮小或糖尿病控制之间存在相关性。需要对用于定义和分期糖尿病患者LJM的方法进行标准化,这一临床发现的意义仍不明确。