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在 30 岁以下的患者中,使用氧化铝-高交联聚乙烯轴承的非骨水泥全髋关节置换术后聚乙烯磨损和骨溶解。

Polyethylene wear and osteolysis after cementless total hip arthroplasty with alumina-on-highly cross-linked polyethylene bearings in patients younger than thirty years of age.

机构信息

The Joint Replacement Center, Ewha Womans University MokDong Hospital, Seoul, Republic of Korea.

出版信息

J Bone Joint Surg Am. 2013 Jun 19;95(12):1088-93. doi: 10.2106/JBJS.L.01211.

DOI:10.2106/JBJS.L.01211
PMID:23783205
Abstract

BACKGROUND

We asked whether cementless total hip arthroplasties that made use of alumina-on-highly cross-linked polyethylene bearings would improve hip score and functional activity and reduce the prevalence of polyethylene wear, osteolysis, and aseptic loosening.

METHODS

Consecutive primary total hip arthroplasties were performed in fifty patients (a total of sixty hips among thirty-four men and sixteen women) who were younger than thirty years of age. The average age at the time of the index arthroplasty was 28.3 years (range, twenty-one to twenty-nine years). The average follow-up was 10.8 years (range, ten to twelve years). Osteolysis and polyethylene wear rates were evaluated with use of radiography and computed tomography.

RESULTS

The mean Harris hip score, which was 38 points (range, 6 to 45 points) preoperatively, had improved to 95 points (range, 85 to 100 points) at a mean follow-up time of 10.8 years. The mean penetration (and standard error of the mean) of the polyethylene liner was 0.031 ± 0.004 mm per year. No hip had osteolysis or aseptic loosening.

CONCLUSIONS

At a minimum of ten years and an average of 10.8 years postoperatively, the current generation of cementless acetabular and femoral components with alumina-on-highly cross-linked polyethylene bearings was functioning well and was not associated with the development of osteolysis in our group of patients younger than thirty years of age. While the long-term prevalence of polyethylene wear and osteolysis remains unknown, the midterm data are promising.

摘要

背景

我们研究了使用氧化铝增强型高交联聚乙烯(alumina-on-highly cross-linked polyethylene)关节面的非骨水泥全髋关节置换术是否可以改善髋关节评分和功能活动,并减少聚乙烯磨损、骨溶解和无菌性松动的发生率。

方法

我们对 50 名(34 名男性和 16 名女性,共 60 髋)年龄小于 30 岁的患者进行了连续初次全髋关节置换术。初次置换时的平均年龄为 28.3 岁(21-29 岁)。平均随访时间为 10.8 年(10-12 年)。采用影像学和计算机断层扫描评估骨溶解和聚乙烯磨损率。

结果

术前平均 Harris 髋关节评分为 38 分(6-45 分),随访 10.8 年后平均提高至 95 分(85-100 分)。聚乙烯衬垫的平均穿透量(及均数的标准误)为每年 0.031 ± 0.004mm。没有髋关节发生骨溶解或无菌性松动。

结论

在至少 10 年且平均 10.8 年的随访后,当前一代的非骨水泥髋臼和股骨组件与氧化铝增强型高交联聚乙烯关节面在我们这组小于 30 岁的患者中表现良好,并未导致骨溶解的发生。虽然聚乙烯磨损和骨溶解的长期发生率尚不清楚,但中期数据令人鼓舞。

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