Scalzo A J, Weber T R, Jaeger R W, Connors R H, Thompson M W
Departments of Pediatrics/Adolescent Medicine, St Louis University School of Medicine, Mo.
Am J Dis Child. 1990 Aug;144(8):867-71. doi: 10.1001/archpedi.1990.02150320031020.
Extracorporeal membrane oxygenation is a pulmonary bypass procedure that has been employed in adults to provide temporary treatment for reversible acute pulmonary and cardiac insufficiency. The technology of membrane oxygenation has been used since 1977 in neonates with predictably fatal pulmonary failure due to respiratory distress syndrome, persistent fetal circulation or persistent pulmonary hypertension of the newborn, meconium aspiration syndrome, and congenital diaphragmatic hernia. The use of extracorporeal membrane oxygenation in older children with other pulmonary disorders has been limited. We report two cases of hydrocarbon aspiration involving petroleum-based products, both successfully treated with extracorporeal membrane oxygenation. A 15-month-old male infant who aspirated baby oil (light mineral oil) is particularly unusual owing to the generally expected low risk of aspiration with a hydrocarbon of such viscosity (greater than 60 Saybolt Universal Seconds). The second patient is a 16-month-old male infant who aspirated furniture polish (mineral seal oil). In both children severe intractable hypoxemia developed despite intensive ventilatory support, and they became candidates for alternative therapy. Extracorporeal membrane oxygenation provides a potentially life-saving option when a patient fails to respond to conventional therapy for hydrocarbon aspiration.
体外膜肺氧合是一种体外循环程序，已用于成人，为可逆性急性肺和心脏功能不全提供临时治疗。自1977年以来，膜肺氧合技术已用于患有因呼吸窘迫综合征、持续性胎儿循环或新生儿持续性肺动脉高压、胎粪吸入综合征和先天性膈疝导致的可预测的致命性肺衰竭的新生儿。体外膜肺氧合在患有其他肺部疾病的大龄儿童中的应用一直有限。我们报告了两例涉及石油基产品的碳氢化合物吸入病例，均成功接受了体外膜肺氧合治疗。一名吸入婴儿油（轻质矿物油）的15个月大男婴尤为特殊，因为对于这种粘度（大于60赛波特通用秒）的碳氢化合物，通常预期吸入风险较低。第二名患者是一名吸入家具上光剂（矿物密封油）的16个月大男婴。尽管进行了强化通气支持，两名儿童均出现了严重的顽固性低氧血症，他们成为了替代治疗的候选者。当患者对碳氢化合物吸入的常规治疗无反应时，体外膜肺氧合提供了一种潜在的挽救生命的选择。
