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基于智能手机的健康附件,用于比色检测汗液和唾液中的生物标志物。

Smartphone based health accessory for colorimetric detection of biomarkers in sweat and saliva.

机构信息

Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA.

出版信息

Lab Chip. 2013 Aug 21;13(16):3232-8. doi: 10.1039/c3lc50431j. Epub 2013 Jun 19.

Abstract

The mobile health market is rapidly expanding and portable diagnostics tools offer an opportunity to decrease costs and increase the availability of healthcare. Here we present a smartphone based accessory and method for the rapid colorimetric detection of pH in sweat and saliva. Sweat pH can be correlated to sodium concentration and sweat rate in order to indicate to users the proper time to hydrate during physical exercise and avoid the risk of muscle cramps. Salivary pH below a critical threshold is correlated with enamel decalcification, an acidic breakdown of calcium in the teeth. We conduct a number of human trials with the device on a treadmill to demonstrate the ability to monitor changes in sweat pH due to exercise and electrolyte intake and predict optimal hydration. Additionally, we perform trials to measure salivary pH over time to monitor the effects of diet on oral health risks.

摘要

移动医疗市场正在迅速扩张,便携式诊断工具为降低成本和增加医疗保健的可及性提供了机会。在这里,我们介绍了一种基于智能手机的附件和方法,用于快速比色检测汗液和唾液中的 pH 值。汗液 pH 值可以与钠离子浓度和出汗率相关联,以向用户指示在体育锻炼过程中适当的补水时间,避免肌肉痉挛的风险。唾液 pH 值低于临界阈值与牙釉质脱矿有关,即牙齿中钙的酸性分解。我们在跑步机上对该设备进行了多次人体试验,以证明其监测运动和电解质摄入引起的汗液 pH 值变化并预测最佳补水的能力。此外,我们还进行了试验以测量随时间变化的唾液 pH 值,以监测饮食对口腔健康风险的影响。

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