Garrett Katherine S, Bramlage Lawrence R, Spike-Pierce Deborah L, Cohen Noah D
Rood and Riddle Equine Hospital, Lexington, KY 40580, USA.
J Am Vet Med Assoc. 2013 Jul 1;243(1):120-5. doi: 10.2460/javma.243.1.120.
To determine the effects of treatment with platelet- and leukocyte-rich plasma (PRP) on future 2-, 3-, and 4-year-old racing performance of yearling Thoroughbreds with proximal sesamoid bone inflammation and associated suspensory ligament branch (SLB) desmitis.
Randomized clinical trial.
39 yearling Thoroughbreds.
Yearling Thoroughbreds with radiographic evidence of performance-limiting proximal sesamoid bone inflammation and ultrasonographic evidence of associated SLB desmitis were identified and randomly assigned to undergo PRP (treatment group) or saline (0.9% NaCl) solution (control group) injection at the affected SLB-proximal sesamoid bone junction. Race records of horses for the 2-, 3-, and 4-year-old racing years were obtained. Data regarding amount of money earned and number of races started were used as outcome measures, and results for groups were compared.
Horses treated with PRP were significantly more likely to start at least 1 race during the 2-year-old racing year than were horses treated with saline solution; no significant differences were detected between groups regarding that variable for the 3- and 4-year-old racing years. No significant differences between groups were detected regarding earnings for any racing year.
Although PRP-treated horses were more likely to start a race during the 2-year-old racing year versus control group horses, results for horses in each group were not significantly different for the 3- and 4-year-old racing years. Therefore, the PRP treatment protocol evaluated in this study did not seem to improve future racing performance of yearling Thoroughbreds with proximal sesamoid bone inflammation and associated SLB desmitis, compared with injection of saline solution.
确定富含血小板和白细胞的血浆（PRP）治疗对患有近籽骨炎症及相关悬韧带分支（SLB）腱炎的一岁纯种赛马未来2岁、3岁和4岁时比赛成绩的影响。
随机临床试验。
39匹一岁纯种赛马。
识别出有影像学证据显示存在限制比赛表现的近籽骨炎症且有超声证据显示存在相关SLB腱炎的一岁纯种赛马，并随机分配至接受PRP（治疗组）或生理盐水（0.9% NaCl）溶液（对照组）注射，注射部位为受影响的SLB - 近籽骨连接处。获取马匹2岁、3岁和4岁比赛年份的比赛记录。将赚取的奖金金额和参赛次数作为结果指标，并比较两组的结果。
与接受生理盐水溶液治疗的马匹相比，接受PRP治疗的马匹在2岁比赛年份至少参加1场比赛的可能性显著更高；在3岁和4岁比赛年份，两组在该变量上未检测到显著差异。在任何比赛年份，两组在收入方面均未检测到显著差异。
尽管与对照组马匹相比，接受PRP治疗的马匹在2岁比赛年份更有可能参加比赛，但在3岁和4岁比赛年份，每组马匹的结果并无显著差异。因此，与注射生理盐水溶液相比，本研究中评估 的PRP治疗方案似乎并未改善患有近籽骨炎症及相关SLB腱炎的一岁纯种赛马未来的比赛成绩。
