Franini Alessio, Entani Maria Grazia, Colosio Elisa, Melotti Luca, Patruno Marco
Sporty Dog Veterinary Clinic, Brescia, Italy.
Department of Comparative Biomedicine and Food Science, University of Padua, Padua, Italy.
Front Vet Sci. 2023 Jan 19;10:1003993. doi: 10.3389/fvets.2023.1003993. eCollection 2023.
In the present case report a 7-year-old male Whippet competing in lure-coursing presented with third-degree recurrent lameness of the right forelimb, pain on palpation of the caudal aspect of the carpus and swelling of the forearm proximally to the accessory carpal bone. Clinical, radiographic, and ultrasonographic evaluation diagnosed a flexor carpi ulnaris (FCU) chronic tendinopathy unresponsive to previously attempted conservative treatments such as oral non-steroidal anti-inflammatory drugs (NSAIDs) administration along with padded palmar splint application and rest. The dog was subjected to one injection of autologous platelet-rich plasma (PRP) obtained using a double centrifugation tube method, followed by two platelet lysate (PL) injections. Treatment was administered at three-week intervals. The healing process was assessed through clinical and ultrasonographic imaging (US) on the day of the first injection (T0), and at week three (T1), six (T2), twelve (T3), fifty-two (T4), and one-hundred-and-four (T5). Fiber alignment score (FAS) and echogenicity score (ES) were developed by modifying a previously published US assessment scale. At T1, ES, and FAS improvement was detected, and at T2, further improvements in ES and FAS were observed. Ultrasonographic results were clinically consistent with the improvement in lameness: lameness grade 3/4 was detected at T0 and grade 2/4 at T1. A lameness grade of 1/4 was detected at T2, and grade 0/4 was observed at T3, T4, and T5. Moreover, at T5, the dog returned to competition, and no history of re-injury was reported. Our results suggest that the treatment of FCU tendinopathy in lure-coursing dogs with a combination of consecutive injections of autologous PRP and PL could be feasible. Additionally, no adverse reactions were observed.
在本病例报告中，一只7岁的雄性惠比特犬在参加诱物追逐赛时出现右前肢三度复发性跛行，腕关节尾侧触诊疼痛，腕副骨近端的前臂肿胀。临床、放射学和超声检查评估诊断为尺侧腕屈肌（FCU）慢性肌腱病，对先前尝试的保守治疗无反应，如口服非甾体抗炎药（NSAIDs）、应用掌侧软垫夹板和休息。该犬接受了一次使用双离心管法获得的自体富血小板血浆（PRP）注射，随后进行了两次血小板裂解物（PL）注射。治疗每隔三周进行一次。在首次注射当天（T0）、第三周（T1）、第六周（T2）、第十二周（T3）、第五十二周（T4）和第一百零四周（T5），通过临床和超声成像（US）评估愈合过程。通过修改先前发表的超声评估量表制定了纤维排列评分（FAS）和回声评分（ES）。在T1时，ES和FAS有所改善，在T2时，ES和FAS进一步改善。超声检查结果在临床上与跛行的改善一致：T0时检测到跛行等级为3/4，T1时为2/4。T2时检测到跛行等级为1/4，T3、T4和T5时为0/4。此外，在T5时，该犬恢复比赛，且未报告再次受伤的病史。我们的结果表明，连续注射自体PRP和PL联合治疗诱物追逐赛犬的FCU肌腱病可能是可行的。此外，未观察到不良反应。
