骨质疏松症的编程及其对骨质疏松症风险的影响。
Programming of osteoporosis and impact on osteoporosis risk.
作者信息
Dennison Elaine M, Harvey Nicholas C, Cooper Cyrus
机构信息
MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, S016 6YD, UK.
出版信息
Clin Obstet Gynecol. 2013 Sep;56(3):549-55. doi: 10.1097/GRF.0b013e31829cb9b0.
Abstract
Osteoporosis is a skeletal disorder characterized by reduced bone quantity and quality and an increased susceptibility to fracture, and seems to be one of many chronic conditions that might be influenced by events early in life. Specifically, there is growing evidence of an interaction between the genome and the environment in the expression of the disease.
摘要
骨质疏松症是一种骨骼疾病，其特征是骨量和骨质量降低，骨折易感性增加，并且似乎是可能受生命早期事件影响的众多慢性病之一。具体而言，越来越多的证据表明，在该疾病的表现中，基因组与环境之间存在相互作用。
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本文引用的文献
1
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J Clin Endocrinol Metab. 2012 Nov;97(11):E2070-7. doi: 10.1210/jc.2012-2538. Epub 2012 Sep 18.
2
Intrauterine growth and postnatal skeletal development: findings from the Southampton Women's Survey.子宫内生长和出生后骨骼发育：来自南安普顿女性调查的发现。
Paediatr Perinat Epidemiol. 2012 Jan;26(1):34-44. doi: 10.1111/j.1365-3016.2011.01237.x.
3
Does birthweight predict bone mass in adulthood? A systematic review and meta-analysis.出生体重能否预测成年后的骨量？系统评价和荟萃分析。
Osteoporos Int. 2011 May;22(5):1323-34. doi: 10.1007/s00198-010-1344-9. Epub 2010 Aug 4.
4
Growth in childhood predicts hip fracture risk in later life.儿童时期的生长发育预测晚年髋部骨折风险。
Osteoporos Int. 2011 Jan;22(1):69-73. doi: 10.1007/s00198-010-1224-3. Epub 2010 Apr 9.
5
Paternal skeletal size predicts intrauterine bone mineral accrual.父亲的骨骼大小可预测宫内骨矿物质的积累。
J Clin Endocrinol Metab. 2008 May;93(5):1676-81. doi: 10.1210/jc.2007-0279. Epub 2008 Feb 19.
6
Intrauterine programming of bone. Part 2: alteration of skeletal structure.
Osteoporos Int. 2008 Feb;19(2):157-67. doi: 10.1007/s00198-007-0448-3. Epub 2007 Aug 18.
7
Growth in early life predicts bone strength in late adulthood: the Hertfordshire Cohort Study.生命早期的生长状况可预测成年后期的骨骼强度：赫特福德郡队列研究
Bone. 2007 Sep;41(3):400-5. doi: 10.1016/j.bone.2007.05.007. Epub 2007 May 31.
8
Placental calcium transporter (PMCA3) gene expression predicts intrauterine bone mineral accrual.胎盘钙转运蛋白（PMCA3）基因表达可预测宫内骨矿物质积累。
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9
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