Meulenbelt J, de Groot G, Savelkoul T J
National Poison Control Centre, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
Br J Ind Med. 1990 Jun;47(6):417-20. doi: 10.1136/oem.47.6.417.
Two patients exposed to high concentrations of toluene in air (greater than 7000 mg/m3) were found at the bottom of a small swimming pool under construction. Their symptoms were stupefaction, paresis, and amnesia. Patient A had been exposed for three hours and patient B for two hours. Ninety minutes after the exposure, the toluene blood concentration in patient A was 4.1 mg/l and in patient B 2.2 mg/l. Urinary ortho-cresol secretion was shown to be a good index of exposure to toluene. After high level exposure, urinary meta-cresol excretion may also be used to monitor toluene exposure.
在一个正在建设的小型游泳池底部发现了两名暴露于空气中高浓度甲苯(超过7000毫克/立方米)的患者。他们的症状是神志不清、轻瘫和失忆。患者A暴露了三小时,患者B暴露了两小时。暴露90分钟后,患者A的甲苯血浓度为4.1毫克/升,患者B为2.2毫克/升。尿邻甲酚分泌被证明是甲苯暴露的一个良好指标。在高剂量暴露后,尿间甲酚排泄也可用于监测甲苯暴露。