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出生窒息与产时胎心监护图

Birth asphyxia and the intrapartum cardiotocograph.

作者信息

Murphy K W, Johnson P, Moorcraft J, Pattinson R, Russell V, Turnbull A

机构信息

Nuffield Department of Obstetrics and Gynaecology, Maternity Department, John Radcliffe Hospital, Headington, Oxford.

出版信息

Br J Obstet Gynaecol. 1990 Jun;97(6):470-9. doi: 10.1111/j.1471-0528.1990.tb02515.x.

Abstract

The intrapartum cardiotocographs (CTGs) of 38 severely asphyxiated, term infants, born during a 17-month period, and those of 120 healthy term infants acting as controls were independently reviewed by three investigators who were unaware of the clinical outcome. Inter-observer agreement was good (Kappa statistic = 0.74, P less than 0.0001). The investigators found that cardiotocographic abnormalities were present in 33 of the asphyxiated infants (87%) and in 35 of the controls (29%) and predicted that the abnormalities were severe enough to lead to significant fetal metabolic acidosis at delivery in 23 asphyxiated infants (61%) and in 11 controls (9%). The differences between the two groups were highly significant (P less than 0.001). Using the traditional diagnostic criteria for fetal distress, the investigators found that fetal blood sampling was indicated in 58% of cases in the asphyxia group and in 20% of controls but was only performed in 16% of asphyxiated infants and in 8% of controls. Furthermore, the median response times of delivery suite staff for abnormal fetal heart rate patterns were similar whether the FHR changes, classified using Krebs' CTG scoring system, were moderate or severe: 80 min and 90 min, respectively. These findings suggest that interpretation of the intrapartum CTG continues to pose major problems for practising obstetricians.

摘要

3名对临床结果不知情的研究人员,对17个月内出生的38名足月重度窒息婴儿以及120名作为对照的足月健康婴儿的产时胎心监护图(CTG)进行了独立评估。观察者间的一致性良好(Kappa统计量=0.74,P<0.0001)。研究人员发现,窒息婴儿中有33例(87%)存在胎心监护异常,对照组中有35例(29%)存在异常;预计有23例窒息婴儿(61%)和11例对照组婴儿(9%)的异常严重到足以导致分娩时出现显著的胎儿代谢性酸中毒。两组之间的差异具有高度显著性(P<0.001)。根据传统的胎儿窘迫诊断标准,研究人员发现,窒息组58%的病例和对照组20%的病例需要进行胎儿血样采集,但仅16%的窒息婴儿和8%的对照组婴儿进行了该项检查。此外,无论使用克雷布斯CTG评分系统分类的胎心率变化是中度还是重度,产房工作人员对异常胎心率模式的中位反应时间相似,分别为80分钟和90分钟。这些发现表明,产时CTG的解读对执业产科医生来说仍然是主要问题。

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