Department of Psychosis Studies, Institute of Psychiatry, King's College London, De Crespigny Park 16, SE58AF London, UK; Section of Psychiatry, Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Psychiatry Res. 2013 Nov 30;210(1):8-15. doi: 10.1016/j.psychres.2013.05.003. Epub 2013 Jun 20.
There is extensive clinical literature reporting traumatic childhood experiences in patients with psychosis. A quantitative meta-analysis addressing the prevalence of self-reported childhood sexual (CSA), physical (CPA) and emotional abuse (CEA) in psychotic patients has yet to be done. We conducted, a systematic literature search to identify retrospective studies addressing self-reported childhood abuse in patients with DSM/ICD psychosis. Demographic, clinical, and methodological variables were extracted from each publication, or obtained directly from its authors. Quantitative meta-analysis of CSA, CPA, CEA in the sample of patients was performed. Statistical heterogeneity and publication bias were assessed and meta-regressions performed to control for different moderators. Twenty-three studies were retrieved and included a total of 2017 psychotic patients. The prevalence of self-reported CSA, CPA, CEA were respectively of 26%, 39% and 34%. Age, publication year, gender and substance abuse moderated CSA, while age, clinical setting and substance abuse moderated CPA. Results indicated that CEA was moderated by gender and publication year of the study. According to our meta-analysis, psychotic patients have a consistently high self-report of childhood traumatic events which are sexual, physical and emotional in nature. It is our opinion that clinicians should be trained and skilled to carefully investigate childhood abuse in psychosis.
大量临床文献报告了精神病患者的创伤性童年经历。目前尚未进行针对精神病患者自我报告的儿童期性虐待（CSA）、身体虐待（CPA）和情感虐待（CEA）患病率的定量荟萃分析。我们进行了系统的文献检索，以确定针对 DSM/ICD 精神病患者自我报告的儿童虐待的回顾性研究。从每篇出版物中提取人口统计学、临床和方法学变量，或直接从其作者处获得。对患者样本中的 CSA、CPA 和 CEA 进行了定量荟萃分析。评估了统计异质性和发表偏倚，并进行了荟萃回归以控制不同的调节因素。检索到 23 项研究，共纳入 2017 名精神病患者。自我报告的 CSA、CPA 和 CEA 的患病率分别为 26%、39%和 34%。年龄、发表年份、性别和物质滥用调节 CSA，而年龄、临床环境和物质滥用调节 CPA。结果表明，CEA 受性别和研究发表年份的调节。根据我们的荟萃分析，精神病患者普遍自我报告有创伤性童年事件，涉及性、身体和情感虐待。我们认为，临床医生应该接受培训并具备熟练的技能，以仔细调查精神病中的儿童虐待问题。
