Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Food Chem. 2013 Nov 15;141(2):1306-12. doi: 10.1016/j.foodchem.2013.03.086. Epub 2013 Apr 16.
Antioxidant activity of different rice extract and the effect on the levels of antioxidant enzyme activity, superoxide dismutase (SOD) and glutathione peroxidase (GPx), vitamin E, lipid peroxidation and liver enzymes in hyperlipidaemia rabbits were investigated. Germinated brown rice (GBR) has the highest antioxidant activity compared to white rice (WR) and brown rice (BR). All rice grains increased the activity of SOD and GPx. However, vitamin E levels increased only in the groups that received the BR and GBR diets. The reduction of lipid peroxidation levels and activity of hepatic enzymes (alanine transferase, ALT and aspartate transaminase, AST) were only significantly observed in the GBR group. In conclusion, GBR supplementation has the greatest impact on increasing antioxidant enzyme activity and vitamin E level and on reducing lipid peroxidation in hypercholesterolaemia rabbit, thereby preventing the formation of atherosclerotic plaques. Furthermore, GBR diet can also reduce the level of hepatic enzymes.
研究了不同米提取物的抗氧化活性及其对高血脂症兔子的抗氧化酶活性、超氧化物歧化酶（SOD）和谷胱甘肽过氧化物酶（GPx）、维生素 E、脂质过氧化和肝酶水平的影响。与白米（WR）和糙米（BR）相比，发芽糙米（GBR）具有最高的抗氧化活性。所有米都增加了 SOD 和 GPx 的活性。然而，只有在接受 BR 和 GBR 饮食的组中，维生素 E 水平才会增加。只有在 GBR 组中，脂质过氧化水平和肝酶（丙氨酸转氨酶，ALT 和天冬氨酸转氨酶，AST）的活性才会显著降低。总之，GBR 补充剂对增加抗氧化酶活性和维生素 E 水平以及降低高血脂症兔子的脂质过氧化作用最大，从而防止动脉粥样硬化斑块的形成。此外，GBR 饮食还可以降低肝酶水平。
