Sipros/ProRata：一个用于定量群落蛋白质组学的多功能信息学系统。
Sipros/ProRata: a versatile informatics system for quantitative community proteomics.
机构信息
Computer Science and Mathematics Division, Oak Ridge National Laboratory and Graduate School of Genome Science and Technology, University of Tennessee-Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
出版信息
Bioinformatics. 2013 Aug 15;29(16):2064-5. doi: 10.1093/bioinformatics/btt329. Epub 2013 Jun 21.
SUMMARY
Sipros/ProRata is an open-source software package for end-to-end data analysis in a wide variety of community proteomics measurements. A database-searching program, Sipros 3.0, was developed for accurate general-purpose protein identification and broad-range post-translational modification searches. Hybrid Message Passing Interface/OpenMP parallelism of the new Sipros architecture allowed its computation to be scalable from desktops to supercomputers. The upgraded ProRata 3.0 performs label-free quantification and isobaric chemical labeling quantification in addition to metabolic labeling quantification. Sipros/ProRata is a versatile informatics system that enables identification and quantification of proteins and their variants in many types of community proteomics studies.
AVAILABILITY
Both programs are freely available under the GNU GPL license at Sipros.omicsbio.org and ProRata.omicsbio.org.
摘要
Sipros/ProRata 是一个开源软件包，可用于各种社区蛋白质组学测量的端到端数据分析。开发了一个数据库搜索程序 Sipros 3.0，用于准确的通用蛋白质鉴定和广泛的翻译后修饰搜索。新 Sipros 架构的混合消息传递接口/OpenMP 并行性允许其计算从桌面扩展到超级计算机。升级后的 ProRata 3.0 除了代谢标记定量外，还执行无标记定量和等压化学标记定量。Sipros/ProRata 是一个通用的信息学系统，可用于鉴定和定量多种类型的社区蛋白质组学研究中的蛋白质及其变体。
可用性
两个程序都可根据 GNU GPL 许可证免费获得，网址分别为 Sipros.omicsbio.org 和 ProRata.omicsbio.org。
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