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[心脏或胃癌患者手术前后的血清睾酮水平]

[Serum testosterone level in patients with cardiac or gastric carcinoma before and after surgery].

作者信息

Lu Z T

机构信息

Jinan Area General Hospital, People's Liberation Army.

出版信息

Zhonghua Wai Ke Za Zhi. 1990 Mar;28(3):178-80, 191.

PMID:2379430
Abstract

Serum testosterone level (STL) was determined in 52 male patients with cardiac carcinoma and in 48 male patients with gastric carcinoma before and after operation, and in 54 normal male subjects and preoperative 40 male patients with benign diseases as control groups. The STL of the patients with cardiac carcinoma or gastric carcinoma was lower than the normal group and the benign diseases group (P less than 0.001, respectively). The postoperative STL of the patients with cardiac or gastric carcinoma was not significantly different from the normal group and the benign diseases group. The STL was lower in patients with recurrence than in the normal group and benign diseases group (P less than 0.001, respectively), and lower in patients with cardiac or gastric carcinoma invading outside the serosa than in those with lesions confined to the musculature (P less than 0.001 and P less than 0.05). Therefore, it appears that the STL may be an important parameter in diagnosis, and in the evaluation of prognosis, postoperative recurrence and resectability of the tumors.

摘要

测定了52例男性贲门癌患者、48例男性胃癌患者手术前后的血清睾酮水平(STL),并以54名正常男性受试者及40例术前男性良性疾病患者作为对照组。贲门癌或胃癌患者的STL低于正常组和良性疾病组(分别为P<0.001)。贲门癌或胃癌患者术后的STL与正常组和良性疾病组无显著差异。复发患者的STL低于正常组和良性疾病组(分别为P<0.001),贲门癌或胃癌侵犯浆膜外的患者的STL低于病变局限于肌层的患者(分别为P<0.001和P<0.05)。因此,STL似乎可能是肿瘤诊断、预后评估、术后复发及可切除性的一个重要参数。

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