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初级保健中筛查出有亚阈抑郁情绪的青少年参与抑郁症预防研究:共病情况及与抑郁症状相关的因素

Adolescents in Primary Care with Sub-Threshold Depressed Mood Screened for Participation in a Depression Prevention Study: Co-Morbidity and Factors Associated with Depressive Symptoms.

作者信息

Van Voorhees Benjamin W, Melkonian Stephanie, Marko Monika, Humensky Jennifer, Fogel Joshua

机构信息

Department of Medicine, The University of Chicago, Chicago, Illinois, USA ; Department of Psychiatry, The University of Chicago, Chicago, Illinois, USA ; Department of Pediatrics, The University of Chicago, Chicago, Illinois, USA.

出版信息

Open Psychiatr J. 2010;4:10-18.

Abstract

PURPOSE

Adolescents in primary care with sub-threshold depression symptoms may be candidates for early intervention to prevent onset of full major depressive disorder. Little is known about this population.

METHOD

We screened consecutive adolescents (ages 14-21) in 13 primary care sites for presence of depression symptoms for "at least a few days" or "nearly every day" in the last two weeks for possible enrollment in a primary care/Internet-based depression prevention intervention (CATCH-IT). We report illness severity, prevalence of self-harm ideation, prevalence correlates (automatic negative thoughts, generalized self-efficacy, perceived social support from family and friends) and co-occurring symptoms of other mental disorders with depressed mood.

RESULTS

Twenty-one percent (N=293) of those screened reported a core symptom of depressive disorder of which 83 enrolled in the study and were analyzed. The sample was 40% ethnic minority with a mean zip code household income of $40,249 (SD=$14,500). Reporting at least one symptom of another mental disorder was common for anxiety (48%, N=40), substance abuse (31%, N=15), conduct disorder (71%, N=53), as were self-harm ideation (16%, N=12) and reporting school impairment (100%, N=83). Prevalence correlates for current depressive symptoms included low self-efficacy, automatic negative thoughts, perceived low peer acceptance, and school impairment.

CONCLUSIONS

Adolescents with sub-threshold depressed mood have frequent co-morbid symptoms that may need to be considered in developing prevention interventions. Early intervention targets to reduce depressed mood include pessimistic thinking, low self-efficacy, low peer acceptance, and school impairment.

摘要

目的

在初级保健机构中,有亚阈值抑郁症状的青少年可能是早期干预以预防重度抑郁症发作的对象。对此人群了解甚少。

方法

我们在13个初级保健机构中对连续的青少年(年龄14 - 21岁)进行筛查,以确定其在过去两周内是否“至少几天”或“几乎每天”存在抑郁症状,筛选出可能符合条件参与一项基于初级保健/互联网的抑郁症预防干预研究(CATCH-IT)的青少年。我们报告了疾病严重程度、自伤意念的患病率、患病率相关因素(自动消极思维、一般自我效能感、来自家人和朋友的感知社会支持)以及与情绪低落同时出现的其他精神障碍症状。

结果

筛查的人群中有21%(N = 293)报告有抑郁症的核心症状,其中83人参与了研究并进行分析。样本中有40%为少数族裔,邮政编码区域家庭平均收入为40,249美元(标准差 = 14,500美元)。报告至少有一种其他精神障碍症状的情况很常见,焦虑症为48%(N = 40),物质滥用为31%(N = 15),品行障碍为71%(N = 53),自伤意念为16%(N = 12),报告学业受损的比例为100%(N = 83)。当前抑郁症状的患病率相关因素包括自我效能感低、自动消极思维、感知到的同伴接纳度低和学业受损。

结论

有亚阈值情绪低落的青少年经常有共病症状,在制定预防干预措施时可能需要考虑这些症状。减轻情绪低落的早期干预目标包括悲观思维、自我效能感低、同伴接纳度低和学业受损。

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