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1984年德意志联邦共和国两个城市中30至64岁人群的药物使用情况。

Drug utilization by the 30-64 year-old people in two cities in the Federal Republic of Germany in 1984.

作者信息

Tennis P

机构信息

GSF-Medis Institut, Department of Epidemiology, Munich, FRG.

出版信息

Eur J Clin Pharmacol. 1990;38(5):447-52. doi: 10.1007/BF02336682.

Abstract

A study has been done to describe and compare the drug utilization profiles of the 30-64 yr-old populations in two cities in the Federal Republic of Germany. Subjects from two community surveys, based on random samples in 1984, from the communities of Augsburg in the south, and Luebeck in the north, were asked to bring to interview any medications taken in the preceding seven days. Total drug use in the two communities was very similar. Women took more drugs than men. The drug categories used by at least 5% of men were analgesics/antirheumatics and antihypertensives. The prevalence of use of different drug categories by men was remarkably similar in the two cities, and the only significant difference was a greater consumption of antihypertensive drugs by Luebeck men (9.8%) compared to Augsburg men (6.3%). The drugs taken by at least 5% of women were sex hormones, analgesics/antirheumatics, antihypertensives, thyroid preparations, psychotropics, cardiac drugs and antihypotensives. Consumption by Augsburg women was significantly greater for sex hormones, cardiac drugs, thyroid drugs, and migraine drugs, whereas Luebeck women consumed significantly more antihypertensives. The high use of thyroid drugs by Augsburg women (11%) is indicative of the high frequency of endemic goitre in the southeastern quarter of the FRG. Although it has been shown from sales data that the FRG has a high consumption of cardiac glycosides, the 6% prevalence of use of preparations of them by 30-64 yr-old Augsburg women represents more precise exposure information and reflects a relatively young group of users.

摘要

一项研究旨在描述和比较德意志联邦共和国两个城市中30至64岁人群的药物使用情况。这两个社区调查的对象是1984年从南部的奥格斯堡社区和北部的吕贝克社区随机抽取的样本,要求他们在接受访谈时带上前七天服用的任何药物。两个社区的药物总使用量非常相似。女性服用的药物比男性多。至少5%的男性使用的药物类别为镇痛药/抗风湿药和抗高血压药。两个城市男性使用不同药物类别的患病率非常相似,唯一显著的差异是吕贝克男性(9.8%)比奥格斯堡男性(6.3%)服用抗高血压药物的消费量更高。至少5%的女性服用的药物为性激素、镇痛药/抗风湿药、抗高血压药、甲状腺制剂、精神药物、心脏药物和抗低血压药。奥格斯堡女性在性激素、心脏药物、甲状腺药物和偏头痛药物方面的消费量显著更高,而吕贝克女性服用抗高血压药物的量显著更多。奥格斯堡女性(11%)甲状腺药物的高使用率表明在德意志联邦共和国东南部地区地方性甲状腺肿的发病率较高。尽管从销售数据来看德意志联邦共和国强心苷的消费量很高,但30至64岁的奥格斯堡女性中6%的人使用强心苷制剂,这代表了更精确的接触信息,也反映出这是一个相对年轻的用户群体。

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