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不孕症治疗中直接腹腔内或宫内授精与超排卵:一项随机研究。

Direct intraperitoneal or intrauterine insemination and superovulation in infertility treatment: a randomized study.

作者信息

Hovatta O, Kurunmäki H, Tiitinen A, Lähteenmäki P, Koskimies A I

机构信息

Finnish Population and Family Welfare Federation, Helsinki, Finland.

出版信息

Fertil Steril. 1990 Aug;54(2):339-41. doi: 10.1016/s0015-0282(16)53714-5.

DOI:10.1016/s0015-0282(16)53714-5
PMID:2379634
Abstract

Direct intraperitoneal or intrauterine insemination in combination with superovulation was used randomly as the treatment of infertility that was unexplained or due to male subfertility or mild endometriosis in 124 couples during 326 cycles. The pregnancy rate per couple was 24% in the direct intraperitoneal insemination group and 31% in the IUI group. The difference was not significant. The pregnancy rates with both treatments were significantly higher than those seen during the 326 control cycles of the same couples (1.1% and 0.6%).

摘要

在326个周期中,对124对夫妇采用直接腹腔内或宫腔内人工授精联合超排卵的方法,随机用于治疗不明原因不孕、男性生育力低下或轻度子宫内膜异位症。直接腹腔内人工授精组每对夫妇的妊娠率为24%,宫腔内人工授精组为31%。差异无统计学意义。两种治疗方法的妊娠率均显著高于同一夫妇的326个对照周期(分别为1.1%和0.6%)。

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Direct intraperitoneal or intrauterine insemination and superovulation in infertility treatment: a randomized study.不孕症治疗中直接腹腔内或宫内授精与超排卵:一项随机研究。
Fertil Steril. 1990 Aug;54(2):339-41. doi: 10.1016/s0015-0282(16)53714-5.
2
Efficacy of superovulation and intrauterine insemination in the treatment of infertility. National Cooperative Reproductive Medicine Network.超排卵及宫腔内人工授精治疗不孕症的疗效。国家合作生殖医学网络。
N Engl J Med. 1999 Jan 21;340(3):177-83. doi: 10.1056/NEJM199901213400302.
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Fertil Steril. 1991 Dec;56(6):1183-7.
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Fertil Steril. 1988 Apr;49(4):602-6. doi: 10.1016/s0015-0282(16)59825-2.
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Low-dose human menopausal gonadotrophin versus clomiphene citrate in subfertile couples treated with intrauterine insemination: a randomized controlled trial.低剂量人绝经期促性腺激素与枸橼酸氯米酚在宫腔内人工授精治疗不孕夫妇中的应用:一项随机对照试验。
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The effects of timing of intrauterine insemination in relation to ovulation and the number of inseminations on cycle pregnancy rate in common infertility etiologies.在常见不孕病因中,宫内授精时机与排卵的关系以及授精次数对周期妊娠率的影响。
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Direct intraperitoneal insemination compared to intrauterine insemination in superovulated cycles: a randomized cross-over study.超排卵周期中腹腔内直接授精与宫腔内授精的比较:一项随机交叉研究。
Gynecol Obstet Invest. 1997;44(3):149-52. doi: 10.1159/000291508.

引用本文的文献

1
An open multicenter study to compare the efficacy of intraperitoneal insemination and intrauterine insemination following multiple follicular development as treatment for unexplained infertility.一项开放性多中心研究,比较多个卵泡发育后腹腔内授精和子宫内授精作为不明原因不孕症治疗方法的疗效。
J Assist Reprod Genet. 1997 Jan;14(1):15-20. doi: 10.1007/BF02765745.
2
In vivo fertilization procedures in infertile women with patent fallopian tubes: a comparison of gamete intrafallopian transfer, combined intrauterine and intraperitoneal insemination, and controlled ovarian hyperstimulation alone.输卵管通畅的不孕女性的体内受精程序:配子输卵管内移植、宫腔内和腹腔内联合授精以及单纯控制性卵巢过度刺激的比较。
J Assist Reprod Genet. 1992 Feb;9(1):19-23. doi: 10.1007/BF01204109.