一项开放性多中心研究，比较多个卵泡发育后腹腔内授精和子宫内授精作为不明原因不孕症治疗方法的疗效。
An open multicenter study to compare the efficacy of intraperitoneal insemination and intrauterine insemination following multiple follicular development as treatment for unexplained infertility.
作者信息
Ajossa S, Melis G B, Cianci A, Coccia M E, Fulghesu A M, Giuffrida G, Guerriero S, Lanzone A, Francoscarselli G
机构信息
Department of Obstetrics and Gynaecology, University of Cagliari, Italy.
出版信息
J Assist Reprod Genet. 1997 Jan;14(1):15-20. doi: 10.1007/BF02765745.
PURPOSE
This multicenter study was carried out to compare the efficacy of intrauterine insemination (IUI) and intraperitoneal insemination (IPI) associated with multiple follicular development as treatment for unexplained infertility.
METHOD
A total of 205 couples completed the trial. Sixty-seven couples underwent treatment with IPI (group A) and 138 couples underwent treatment with IUI (group B).
RESULTS
Clinical pregnancy was obtained in 23 couples in group A (pregnancy rate: 34.3%) and in 36 couples in group B (pregnancy rate: 26.1%). No significant difference was observed between group A and group B. As for the evolution of pregnancies and the incidence of twin pregnancies, no significant difference was observed between the two groups.
CONCLUSIONS
Because IUI and IPI allow us to obtain same results and IPI is more invasive than IUI, the latter technique can be considered the method of choice and IPI should be used when IUI is difficult to perform, as in the presence of a tight cervical canal.
目的
本多中心研究旨在比较宫腔内人工授精（IUI）和腹腔内人工授精（IPI）联合多个卵泡发育作为不明原因不孕症治疗方法的疗效。
方法
共有205对夫妇完成了该试验。67对夫妇接受IPI治疗（A组），138对夫妇接受IUI治疗（B组）。
结果
A组23对夫妇临床妊娠（妊娠率：34.3%），B组36对夫妇临床妊娠（妊娠率：26.1%）。A组和B组之间未观察到显著差异。至于妊娠进展和双胎妊娠发生率，两组之间未观察到显著差异。
结论
由于IUI和IPI能取得相同的结果，且IPI比IUI更具侵入性，后者技术可被视为首选方法，而当IUI难以实施时，如宫颈管狭窄时，应使用IPI。
Zotero 插件