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一项为期五年的关于颗粒物(PM2.5)与脑血管病的研究。

A five-year study of particulate matter (PM2.5) and cerebrovascular diseases.

机构信息

Centro de Ciencias Ambientales and Departamento de Química, Facultad de Ciencias, Universidad de Chile, Casilla 653, Santiago, Chile.

出版信息

Environ Pollut. 2013 Oct;181:1-6. doi: 10.1016/j.envpol.2013.05.057. Epub 2013 Jun 22.

Abstract

Cerebrovascular accidents, or strokes, are the second leading cause of mortality and the leading cause of morbidity in both Chile and the rest of the world. However, the relationship between particulate matter pollution and strokes is not well characterized. The association between fine particle concentration and stroke admissions was studied. Data on hospital admissions due to cerebrovascular accidents were collected from the Ministry of Health. Air quality and meteorological data were taken from the Air Quality database of the Santiago Metropolitan Area. Santiago reported 33,624 stroke admissions between January 1, 2002 and December 30, 2006. PM2.5 concentration was markedly seasonal, increasing during the winter. This study found an association between PM2.5 exposure and hospital admissions for stroke; for every PM2.5 concentration increase of 10 μg m(-3), the risk of emergency hospital admissions for cerebrovascular causes increased by 1.29% (95% CI 0.552%-2.03%).

摘要

脑血管意外,又称中风,是智利乃至全球第二大致死原因和首要致残原因。然而,目前对于颗粒物污染与中风之间的关系还不甚清楚。本研究旨在探讨细颗粒物浓度与中风入院之间的关系。研究人员从智利卫生部收集了因脑血管意外入院的数据,从圣地亚哥大都市区空气质量数据库中获取了空气质量和气象数据。报告显示,2002 年 1 月 1 日至 2006 年 12 月 30 日期间,圣地亚哥共有 33624 例中风入院。PM2.5 浓度呈明显季节性变化,冬季升高。本研究发现 PM2.5 暴露与中风住院之间存在关联;每增加 10μg/m3 的 PM2.5 浓度,因脑血管原因紧急住院的风险增加 1.29%(95%CI 0.552%-2.03%)。

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