Welch Center for Prevention, Epidemiology and Clinical Research Department of Epidemiology, Bloomberg School of Public Health Johns Hopkins University, Baltimore, Maryland, 21205, USA.
Center for Disease Control and Prevention of Yinzhou District, Ningbo, 215100, Zhejiang, China.
Environ Sci Pollut Res Int. 2019 Apr;26(12):12280-12287. doi: 10.1007/s11356-019-04397-7. Epub 2019 Mar 6.
Fine particulate matter (PM) is a mixture of multiple components, which is associated with several chronic diseases, including respiratory and cardiovascular diseases. We evaluated the association between daily PM and PM exposure and hospital visits for respiratory diseases. Hospital visits for respiratory diseases were collected from Yinzhou Health Information System database. We used generalized additive models to examine the excess relative risk (ERR) and 95% confidence interval for hospital visits for respiratory diseases associated with each 10-μg/m increase in PM and PM concentration. Non-linear exposure-response relationship between PM exposure and hospital visits for respiratory diseases was evaluated by a smooth spline. The ERRs for hospital visits for respiratory diseases associated with a 10-μg/m increase in the 6-day cumulative average concentration of PM and PM were 5.40 (95% CI 2.32, 8.57) and 6.37% (95% CI 1.84, 11.10), respectively. The findings remained stable when we adjusted other gaseous air pollution. PM and PM were associated with the increased visits for the acute upper respiratory infection, pneumonia, asthma, and COPD. In this time-series study, we found a positive association between daily particulate matter exposure and hospital visits for respiratory diseases.
细颗粒物（PM）是多种成分的混合物，与多种慢性疾病有关，包括呼吸道和心血管疾病。我们评估了每日 PM 和 PM 暴露与呼吸道疾病住院就诊之间的关系。呼吸道疾病住院就诊数据从鄞州卫生信息系统数据库中收集。我们使用广义加性模型，以检验与每增加 10μg/m 的 PM 和 PM 浓度相关的呼吸道疾病住院就诊的超额相对风险（ERR）和 95%置信区间。通过平滑样条来评估 PM 暴露与呼吸道疾病住院就诊之间的非线性暴露-反应关系。与 PM 浓度的 6 天累积平均值增加 10μg/m 相关的呼吸道疾病住院就诊的 ERR 分别为 5.40（95%CI 2.32，8.57）和 6.37%（95%CI 1.84，11.10）。当我们调整其他气态空气污染物时，结果仍然稳定。PM 和 PM 与急性上呼吸道感染、肺炎、哮喘和 COPD 的就诊次数增加有关。在这项时间序列研究中，我们发现每日颗粒物暴露与呼吸道疾病住院就诊之间存在正相关关系。
