Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Curr Allergy Asthma Rep. 2013 Aug;13(4):354-60. doi: 10.1007/s11882-013-0357-9.
Sjögren's syndrome (SS) is primarily defined by its impact on the oral and ocular system resulting in xerostomia and xerophthalmia. However, SS can also manifest throughout the respiratory system. Subclinical pulmonary involvement is common. Clinically significant involvement can result in a 4-fold increased risk of death. Thus, recognizing the many potential presentations of SS in the lung is critical in caring for patients with SS. Additionally, SS should be included in the differential diagnosis of a number of forms of interstitial lung disease.
干燥综合征(SS)主要是由其对口腔和眼部系统的影响导致的口干症和干眼病来定义的。然而,SS 也可以在整个呼吸系统中表现出来。亚临床肺部受累很常见。有临床意义的肺部受累会导致死亡风险增加 4 倍。因此,在治疗 SS 患者时,识别肺部 SS 的许多潜在表现至关重要。此外,SS 应纳入多种间质性肺疾病的鉴别诊断。