Department of Kinesiology, University of Massachusetts-Amherst, Amherst, Massachusetts, USA.
Compr Physiol. 2012 Apr;2(2):997-1044. doi: 10.1002/cphy.c110029.
Skeletal muscle fatigue is defined as the fall of force or power in response to contractile activity. Both the mechanisms of fatigue and the modes used to elicit it vary tremendously. Conceptual and technological advances allow the examination of fatigue from the level of the single molecule to the intact organism. Evaluation of muscle fatigue in a wide range of disease states builds on our understanding of basic function by revealing the sources of dysfunction in response to disease.
骨骼肌疲劳是指在收缩活动时力量或功率的下降。疲劳的机制和诱发疲劳的方式变化非常大。概念和技术的进步使得我们能够从单个分子水平到完整生物体水平来检查疲劳。对广泛疾病状态下肌肉疲劳的评估通过揭示疾病反应中功能障碍的来源，建立在我们对基本功能的理解之上。
