980nm 激光驱动光热载体实现疏水性抗癌药物传递，用于高效协同治疗体内癌细胞。
Hydrophobic anticancer drug delivery by a 980 nm laser-driven photothermal vehicle for efficient synergistic therapy of cancer cells in vivo.
机构信息
Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Changchun, Jilin, China.
出版信息
Adv Mater. 2013 Aug 27;25(32):4452-8. doi: 10.1002/adma.201301232. Epub 2013 Jun 25.
PMID:23798450
Abstract
A novel 980 nm laser-driven hydrophobic anticancer drug-delivery platform based on hollow CuS nanoparticles is constructed in this work. The excellent synergistic therapy combining drug treatment and photothermal ablation of cancer cells both in vitro and in vivo is demonstrated, which opens up new opportunities for biological and medical applications.
摘要
本工作构建了一种基于中空 CuS 纳米粒子的新型 980nm 激光驱动疏水性抗癌药物输送平台。体外和体内实验均证明了药物治疗和光热消融癌细胞的协同治疗效果显著，为生物医学应用开辟了新的机会。
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