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一种新型草药百里香与传统化学药物布洛芬相比对原发性痛经的影响。

The impact of a novel herbal Shirazi Thymus Vulgaris on primary dysmenorrhea in comparison to the classical chemical Ibuprofen.

作者信息

Direkvand-Moghadam Ashraf, Khosravi Afra

机构信息

Department of Immunology, Ilam University of Medical Sciences, Ilam, Iran.

出版信息

J Res Med Sci. 2012 Jul;17(7):668-70.

Abstract

OBJECTIVE

Primary dysmenorrhea is defined as painful cramps during menstruation with no pelvic pathology. Due to the adverse effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are considered as the most common pharmacological treatment for this disorder. The present study was conducted to assess the impact of Shirazi Thymus Vulgaris compared to that of Ibuprofen on primary dysmenorrhea.

MATERIALS AND METHODS

A randomized, single-blind clinical trial was conducted amongst 120 female students ofIlam University of Medical Sciences, aged 18-25 years who suffered from primary dysmenorrhea. The participants were randomly divided into two groups; one received the herbal and the other classical treatments. The herbal group received 5 ml of the Shirazi Thymus Vulgaris medication that commercially called BronchoT.D, orally four times a day. The classic group received Ibuprofen orally three times a day. A visual analogue scale (VAS) was used to record pain severity.

RESULTS

Pain severity was reduced in both herbal and classic groups with no significant differences. Pain duration at the first and second month of treatment was also similar between two groups.

CONCLUSIONS

Shirazi Thymus Vulgaris decreased dysmenorrhea symptoms, which might be attributed to its antispasmodic effects. The herbal Shirazi Thymus Vulgaris can be recommended as an effective medication fortreatment of the primary dysmenorrhea disorder.

摘要

目的

原发性痛经被定义为月经期间无盆腔病变的疼痛性痉挛。由于非甾体抗炎药的不良反应,其被认为是该疾病最常见的药物治疗方法。本研究旨在评估与布洛芬相比,伊朗百里香对原发性痛经的影响。

材料与方法

对120名年龄在18 - 25岁、患有原发性痛经的伊拉姆医科大学女学生进行了一项随机、单盲临床试验。参与者被随机分为两组;一组接受草药治疗,另一组接受传统治疗。草药组每天口服4次5毫升商业名为BronchoT.D的伊朗百里香药物。经典组每天口服3次布洛芬。使用视觉模拟量表(VAS)记录疼痛严重程度。

结果

草药组和经典组的疼痛严重程度均降低,且无显著差异。两组治疗第一个月和第二个月的疼痛持续时间也相似。

结论

伊朗百里香可减轻痛经症状,这可能归因于其解痉作用。伊朗百里香草药可作为治疗原发性痛经疾病的有效药物推荐使用。

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