Department of Otorhinolaryngology-Head and Neck Surgery, Chuncheon Sacred Heart Hospital, Chuncheon, Korea. ; Nano Bio Regenerative Medical Institute, Hallym University College of Medicine, Chuncheon, Korea.
Clin Exp Otorhinolaryngol. 2013 Jun;6(2):78-81. doi: 10.3342/ceo.2013.6.2.78. Epub 2013 Jun 14.
The clinical features of various facial deformities in Korean leprosy patients were evaluated according to the type of leprosy.
One hundred ninety six patients with leprosy were examined for various facial deformities using a nasal speculum, endoscope, and digital camera. The frequency and severity of external nasal deformities and septal perforations were evaluated according to the type of leprosy. Eye deformities, ear deformities, and facial palsy were also assessed.
Seventy-one patients (36.2%) displayed external nasal deformities: 28 minimal contractures, three cartilage contractures, two bony-cartilage contractures, and 38 skin defects. The external nasal deformity and severe form deformity in lepromatous types were more frequent compared to other types (P<0.05 for each variable). Twenty-three patients (9%) displayed septal perforations, among whom 11 had cartilaginous perforations and 12 had bony-cartilaginous perforations. The frequency of septal and bony-cartilaginous perforations did not differ significantly between the types of leprosy (P>0.05 for each variable). Sixty-one patients (31.1%) had eye deformities and 19 patients (9.7%) had facial nerve palsy, common in the borderline type. No cases of ear deformities were observed.
Korean patients had characteristic deformities according to the type of leprosy. They were different from those seen in the prior analyses of Caucasian populations.
根据麻风病类型评估韩国麻风病患者各种面部畸形的临床特征。
使用鼻窥镜、内窥镜和数码相机检查 196 例麻风病患者的各种面部畸形。根据麻风病类型评估外部鼻畸形和鼻中隔穿孔的频率和严重程度。还评估了眼部畸形、耳部畸形和面瘫。
71 例患者(36.2%)出现外部鼻畸形:28 例轻微挛缩、3 例软骨挛缩、2 例骨软骨挛缩和 38 例皮肤缺损。瘤型麻风的外部鼻畸形和严重型畸形比其他类型更常见(每种变量的 P<0.05)。23 例患者(9%)出现鼻中隔穿孔,其中 11 例为软骨穿孔,12 例为骨软骨穿孔。各种麻风病类型之间鼻中隔和骨软骨穿孔的频率无显著差异(每种变量的 P>0.05)。61 例患者(31.1%)存在眼部畸形,19 例患者(9.7%)存在面神经麻痹,交界型较常见。未观察到耳部畸形。
韩国患者根据麻风病类型存在特征性畸形。它们与之前对高加索人群的分析中观察到的畸形不同。