Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2013 Jun;6(2):107-9. doi: 10.3342/ceo.2013.6.2.107. Epub 2011 Oct 1.
Sclerosing polycyctic adenosis (SPA) is a rare lesion of unknown etiology morphologically resembling fibrocystic changes of the breast. To date, approximately 41 cases of SPA have been reported. Most cases of SPA have originated in the parotid and submandibular glands, with a few cases of intra-oral minor salivary gland origin. This is the first reported case of sclerosing polycystic adenosis of nasal minor salivary gland origin. The differential diagnosis of SPA includes polycystic disease, sclerosing sialadenitis, and benign and malignant glandular neoplasias. Although atypia ranging from mild dysplasia to carcinoma in situ can occur in some cases, SPA has a favorable outcome. It is important to be familiar with SPA to avoid aggresive treatment that results from a misdiagnosis. We present a case of a 49-year-old man who had 1-year history of right nasal obstruction.
硬化性多囊性腺病（SPA）是一种罕见的病因不明的病变，在形态上类似于乳腺的纤维囊性改变。迄今为止，大约有 41 例 SPA 被报道。大多数 SPA 起源于腮腺和颌下腺，少数起源于口腔小唾液腺。这是首例报道的源于鼻腔小唾液腺的硬化性多囊性腺病。SPA 的鉴别诊断包括多囊性疾病、硬化性唾液腺炎以及良性和恶性腺肿瘤。虽然在一些病例中可能会出现从轻度异型增生到原位癌的异型，但 SPA 的预后良好。熟悉 SPA 对于避免因误诊而导致的激进治疗非常重要。我们报告了 1 例 49 岁男性患者，他有 1 年的右侧鼻腔阻塞病史。
