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非囊性硬化性多囊腺病:一种此前未描述模式的诊断

Non-cystic Sclerosing Polycystic Adenosis: Diagnosis of a Hitherto Undescribed Pattern.

作者信息

Petersson Fredrik

机构信息

Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.

出版信息

Head Neck Pathol. 2019 Dec;13(4):681-685. doi: 10.1007/s12105-018-0979-2. Epub 2018 Oct 25.

Abstract

A case of sclerosing polycystic adenosis without cysts is described. The lesion occurred as a painless slow growing superficial right parotid lump in a 47 years old woman. The tumor measured 14 × 10 mm and displayed extreme well circumscription, sclerotic stroma with scattered hyaline nodules, sprinkling of mononuclear inflammatory cells and islands of mature fat. The epithelial component was predominantly composed of tubules lined by low columnar to cuboidal epithelium with bland nuclear features. Only focal incomplete acinar differentiation with few cells containing small eosinophilic granules was present. The stroma contained a significant fibromyxoid component with increased cellularity. There was no recurrence on follow-up at 14 months.

摘要

本文描述了一例无囊肿的硬化性多囊腺病病例。该病变表现为一名47岁女性右侧腮腺浅表无痛性缓慢生长肿块。肿瘤大小为14×10毫米,边界极为清晰,有硬化性间质,散在透明结节,少量单核炎性细胞浸润以及成熟脂肪岛。上皮成分主要由低柱状至立方上皮衬覆的小管组成,细胞核形态温和。仅见局灶性不完全腺泡分化,少数细胞含有小嗜酸性颗粒。间质含有大量纤维黏液样成分,细胞增多。随访14个月无复发。

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