McGue M, Borecki I B, Gerrard J W, Rao D C
Department of Psychology, University of Minnesota, Minneapolis.
Hum Hered. 1990;40(4):231-4. doi: 10.1159/000153935.
Evidence for a sex-linked determinant of immunoglobulin M levels was sought using correlational and commingling analyses in a sample of 174 randomly selected nuclear families. While mean IgM levels in females were approximately 25% higher than that in males, the pattern of familial correlations did not follow the expectations under a sex-linked model, and there was no commingling in the distribution of IgM levels as expected when a trait is under the influence of a major gene.
在一个由174个随机选择的核心家庭组成的样本中，通过相关性分析和混合分析，寻找免疫球蛋白M水平的性连锁决定因素的证据。虽然女性的平均免疫球蛋白M水平比男性高约25%，但家族相关性模式并不符合性连锁模型下的预期，并且当一个性状受一个主基因影响时，免疫球蛋白M水平的分布也没有如预期那样出现混合现象。
