Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.
BMC Pediatr. 2013 Jun 24;13:99. doi: 10.1186/1471-2431-13-99.
Given that it is not feasible to use dual x-ray absorptiometry (DXA) or other reference methods to measure adiposity in all pediatric clinical and research settings, it is important to identify reasonable alternatives. Therefore, we sought to determine the extent to which other adiposity measures were correlated with DXA fat mass in school-aged children.
In 1110 children aged 6.5-10.9 years in the pre-birth cohort Project Viva, we calculated Spearman correlation coefficients between DXA (n=875) and other adiposity measures including body mass index (BMI), skinfold thickness, circumferences, and bioimpedance. We also computed correlations between lean body mass measures.
50.0% of the children were female and 36.5% were non-white. Mean (SD) BMI was 17.2 (3.1) and total fat mass by DXA was 7.5 (3.9) kg. DXA total fat mass was highly correlated with BMI (r(s)=0.83), bioimpedance total fat (r(s)=0.87), and sum of skinfolds (r(s)=0.90), and DXA trunk fat was highly correlated with waist circumference (r(s)=0.79). Correlations of BMI with other adiposity indices were high, e.g., with waist circumference (r(s)=0.86) and sum of subscapular plus triceps skinfolds (r(s)=0.79). DXA fat-free mass and bioimpedance fat-free mass were highly correlated (r(s)=0.94).
In school-aged children, BMI, sum of skinfolds, and other adiposity measures were strongly correlated with DXA fat mass. Although these measurement methods have limitations, BMI and skinfolds are adequate surrogate measures of relative adiposity in children when DXA is not practical.
鉴于在所有儿科临床和研究环境中使用双能 X 射线吸收法（DXA）或其他参考方法来测量肥胖是不可行的，因此确定合理的替代方法非常重要。因此，我们试图确定其他肥胖测量值与学龄儿童 DXA 脂肪量之间的相关性程度。
在 Pre-birth 队列项目 Viva 的 1110 名 6.5-10.9 岁的儿童中，我们计算了 DXA（n=875）与其他肥胖测量值（包括体重指数（BMI）、皮褶厚度、周长和生物阻抗）之间的 Spearman 相关系数。我们还计算了瘦体重测量值之间的相关性。
50.0%的儿童为女性，36.5%为非白人。平均（SD）BMI 为 17.2（3.1），DXA 总脂肪量为 7.5（3.9）kg。DXA 总脂肪量与 BMI（r(s)=0.83）、生物阻抗总脂肪（r(s)=0.87）和皮褶总和（r(s)=0.90）高度相关，DXA 躯干脂肪与腰围（r(s)=0.79）高度相关。BMI 与其他肥胖指数的相关性很高，例如与腰围（r(s)=0.86）和肩胛下角加肱三头肌皮褶总和（r(s)=0.79）。DXA 去脂体重和生物阻抗去脂体重高度相关（r(s)=0.94）。
在学龄儿童中，BMI、皮褶总和和其他肥胖测量值与 DXA 脂肪量密切相关。虽然这些测量方法存在局限性，但在 DXA 不切实际的情况下，BMI 和皮褶是儿童相对肥胖的足够替代指标。
