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重症呼吸护理服务。组织、定位、系统与未来。我们对288例病例的管理经验。

Intensive respiratory care service. Organisation, orientation, system and future. Our experience of management of 288 cases.

作者信息

Shah A C, Trivedi A M, Vishwanath N, Pajankar S P, Nabar S T, Bhambure N, Deshmukh S N

机构信息

Department of Respiratory Diseases, L.T.M.G. Hospital, Sion, Bombay.

出版信息

J Assoc Physicians India. 1990 Feb;38(2):140-3.

PMID:2380133
Abstract

Between Jan. 1983 and Dec. 1986, 288 patients with acute respiratory failure of varied aetiologies were admitted to tetanus and respiratory care ward. One hundred and twenty patients (41.66%) had primary respiratory diseases, 107 (37.15%) of poisoning, 24 (8.3%) had neuromuscular diseases and 37 (12.48%) had miscellaneous disorders. Ventilatory support was given for more than 6 hours to 118 patients. The overall survival was 61.81% and on ventilator 38.13%. The mortality was high with ARDS (100%), miscellaneous (100%) pneumonia with septicaemia (75%) and COAD (54.28%). Patient with COAD had high mortality with acidosis (pH less than 7.1, P less than 0.01), hypotension (systolic BP less than 90 mm of Hg, p less than 0.05) and oliguria (urine out put less than 400 ml/24 hours, p less than 0.05). Organophosphorus compound was the commonest poison (89.75%) and patients who had moderate to severe hypoxia (pO2 less than 60 mm of Hg), hypotension and an interval of more than 4 hours between the consumption of poison and admission (all P less than 0.05) expired; 68.18% expired within the first 72 hours. All the patients with primary neuromuscular paralysis and bronchial asthma survived. Hospital acquired infections (160 patients), retained secretions (108 patients) and hypotension (64 patients) were the commonest complications seen in the 288 patients. Staphylococcus aureus (32.14%) was the commonest organism isolated. Financial constraints, drug shortages and frequent failure of machines were other major problems in the intensive respiratory care unit.

摘要

1983年1月至1986年12月期间,288例病因各异的急性呼吸衰竭患者被收治于破伤风与呼吸监护病房。120例患者(41.66%)患有原发性呼吸系统疾病,107例(37.15%)为中毒,24例(8.3%)患有神经肌肉疾病,37例(12.48%)患有其他杂症。118例患者接受了超过6小时的通气支持。总体生存率为61.81%,使用呼吸机的生存率为38.13%。急性呼吸窘迫综合征(ARDS)的死亡率为100%,其他杂症、伴有败血症的肺炎(75%)以及慢性阻塞性肺疾病(COAD,54.28%)的死亡率较高。患有COAD的患者在出现酸中毒(pH值小于7.1,P小于0.01)、低血压(收缩压小于90毫米汞柱,p小于0.05)和少尿(尿量小于400毫升/24小时,p小于0.05)时死亡率较高。有机磷化合物是最常见的毒物(89.75%),出现中度至重度缺氧(动脉血氧分压小于60毫米汞柱)、低血压以及中毒与入院间隔超过4小时的患者(所有P值均小于0.05)死亡;68.18%的患者在最初72小时内死亡。所有原发性神经肌肉麻痹和支气管哮喘患者均存活。医院获得性感染(160例患者)、分泌物潴留(108例患者)和低血压(64例患者)是这288例患者中最常见的并发症。分离出的最常见病原体是金黄色葡萄球菌(32.14%)。资金限制、药品短缺和设备频繁故障是重症呼吸监护病房的其他主要问题。

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