Hauser M J, Tabak J, Baier H
Arch Intern Med. 1982 Mar;142(3):527-9.
The records of 40 patients with cancer and 684 patients without cancer admitted to a medical critical care unit were reviewed for the purpose of comparing survival. Patients with cancer had a higher mortality (55%, 22/40) than the patients without cancer (17%, 118/864). Patients with cancer and respiratory failure had a higher mortality (75%, 18/24) than patients without cancer but with respiratory failure (25%, 66/273) and a higher mortality than patients with cancer but without respiratory failure (25%, 4/16). In patients with cancer, the manifestation of respiratory failure as the adult respiratory distress syndrome (ARDS) was associated with a high mortality (86%, 12/14), which was not statistically higher than in patients with cancer with non-ARDS respiratory failure (60%, 6/10) or in patients without cancer with ARDS (65%, 28/43). Patients with cancer but without respiratory failure had a mortality of 25% (4/16). All eight patients with cancer admitted to the hospital because of life-threatening metabolic disturbances survived. In deciding whether to apply critical care techniques to a patient with cancer, the physician should consider the specific nature of the life-threatening illness.
为比较生存率,对入住医疗重症监护病房的40例癌症患者和684例非癌症患者的记录进行了回顾。癌症患者的死亡率(55%,22/40)高于非癌症患者(17%,118/864)。患有癌症且伴有呼吸衰竭的患者死亡率(75%,18/24)高于没有癌症但伴有呼吸衰竭的患者(25%,66/273),且高于患有癌症但没有呼吸衰竭的患者(25%,4/16)。在癌症患者中,表现为成人呼吸窘迫综合征(ARDS)的呼吸衰竭与高死亡率相关(86%,12/14),这在统计学上并不高于患有非ARDS呼吸衰竭的癌症患者(60%,6/10)或患有ARDS的非癌症患者(65%,28/43)。患有癌症但没有呼吸衰竭的患者死亡率为25%(4/16)。因危及生命的代谢紊乱入院的所有8例癌症患者均存活。在决定是否对癌症患者应用重症监护技术时,医生应考虑危及生命疾病的具体性质。