Austin L S, Arana G W, Melvin J A
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29464.
J Clin Psychiatry. 1990 Aug;51(8):344-5.
Lithium augmentation of antidepressant treatment is a commonly used strategy for treatment-resistant cases of depression. Two cases are described in which significant neurotoxicity developed in elderly patients despite therapeutic doses of antidepressant and lithium.
锂盐增效抗抑郁治疗是治疗难治性抑郁症常用的策略。本文描述了两例老年患者,尽管使用了治疗剂量的抗抑郁药和锂盐,但仍出现了显著的神经毒性。