Department of Anatomy, Histology, Legal Medicine and Orthopedics, Unit of Occupational Medicine, University of Rome Sapienza, Rome, Italy.
J Environ Sci Health A Tox Hazard Subst Environ Eng. 2013;48(12):1457-69. doi: 10.1080/10934529.2013.796769.
The aim of the study was to assess the relationship between occupational exposure to airborne lead (Pb) and alterations in peripheral blood counts in workers of the Municipal Police assigned to different types of outdoor tasks. Then, 337 both male and female subjects were enrolled and divided on the basis of sex, cigarette smoking habit and kind of task. Exposure to airborne Pb, dosage of total blood Pb and peripheral blood count were carried out. A significant positive correlation was detected between the values of total blood Pb and values of plasma reticulocytes (%RET) both in the total sample and for all the classes of the subdivision except for police drivers. Some statistically significant correlations were present but discontinuous for other variables of peripheral blood counts. Results suggest that occupational exposure to low doses of airborne Pb is able to influence lines of the hematopoietic system in exposed workers, with special reference to %RET.
本研究旨在评估市警中从事不同户外任务的工作人员，其职业性空气铅（Pb）暴露与外周血象改变之间的关系。随后，招募了 337 名男性和女性受试者，并根据性别、吸烟习惯和任务类型进行分组。对空气中 Pb 的暴露、全血 Pb 的剂量和外周血计数进行了检测。在总样本以及除警察驾驶员外的所有细分组中，均检测到全血 Pb 值与网织红细胞（%RET）值之间存在显著正相关。在外周血象的其他变量中，也存在一些统计学上显著但不连续的相关性。结果表明，职业性低剂量空气 Pb 暴露能够影响暴露工人的造血系统，特别是 %RET。
