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三例卵巢甲状腺肿患者在术前明确诊断后接受了腹腔镜手术。

Three cases of struma ovarii underwent laparoscopic surgery with definite preoperative diagnosis.

作者信息

Kusumoto Tomoyuki, Inoue Seiji, Nakamura Keiichiro, Seki Noriko, Hongo Atsushi, Kodama Junichi, Hiramatsu Yuji

机构信息

Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.

出版信息

Acta Med Okayama. 2013;67(3):191-5. doi: 10.18926/AMO/50413.

Abstract

Struma ovarii is a rare neoplasm that accounts for approximately 0.3% of ovarian tumors. Due to its ultrasound morphology, which is quite similar to that of malignant ovarian carcinoma, most struma ovarii cases are open operated with laparotomy rather than laparoscopy. We present 3 cases of struma ovarii, which were diagnosed preoperatively by imaging studies and removed by laparoscopic surgery. All patients were premenopausal women between ages 31‒50. The magnetic resonance imaging (MRI) findings were complex masses composed of multiple cysts and solid components with T2-hypointense regions as well as multiple T1-hyperintense cystic areas, findings that are typical for struma ovarii. A combination of plain computed tomography (CT), positron emission tomography (PET)-CT, and scintigraphy was useful for diagnosis. Laboratory examination revealed elevated serum thyroglobulin, which led to the diagnosis of struma ovarii. Laparoscopic surgeries were performed without rupturing the tumors. Although it has been difficult to differentiate between struma ovarii and malignant tumors by conventional methods, recently MRI techniques appear make it possible to diagnose struma ovarii preoperatively from the abovementioned imaging characteristic, together with laboratory data. As for treatment, we think laparoscopy could be successful for struma ovarii, but the surgeon must be careful not to rupture the tumor intra-abdominally in order to prevent dissemination, which could lead to malignancy.

摘要

卵巢甲状腺肿是一种罕见的肿瘤,约占卵巢肿瘤的0.3%。由于其超声形态与恶性卵巢癌非常相似,大多数卵巢甲状腺肿病例采用剖腹手术而非腹腔镜手术。我们报告3例卵巢甲状腺肿病例,术前通过影像学检查确诊,并通过腹腔镜手术切除。所有患者均为31至50岁的绝经前女性。磁共振成像(MRI)表现为多个囊肿和实性成分组成的复杂肿块,伴有T2低信号区以及多个T1高信号囊性区域,这些表现是卵巢甲状腺肿的典型特征。普通计算机断层扫描(CT)、正电子发射断层扫描(PET)-CT和闪烁扫描相结合有助于诊断。实验室检查显示血清甲状腺球蛋白升高,从而确诊为卵巢甲状腺肿。腹腔镜手术在不破裂肿瘤的情况下进行。尽管通过传统方法难以区分卵巢甲状腺肿和恶性肿瘤,但最近MRI技术似乎能够根据上述影像学特征以及实验室数据在术前诊断卵巢甲状腺肿。至于治疗,我们认为腹腔镜手术对卵巢甲状腺肿可能成功,但外科医生必须小心避免在腹腔内弄破肿瘤,以防止播散,这可能导致恶变。

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