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伴假性梅格斯综合征及癌抗原-125水平升高伪装成卵巢癌:病例报告及文献综述

with Pseudo-Meigs' Syndrome and Raised Cancer Antigen-125 Levels Masquerading as an Ovarian Carcinoma Case report and literature review.

作者信息

Yadav Surekha, Tomar Reena, Verma Nidhi, Khurana Nita, Triathi Rewa

机构信息

Department of Pathology, Maulana Azad Medical College, New Delhi, India.

Department of Obstetrics & Gynecology, Lok Nayak Jai Prakash Narayan Hospital, New Delhi, Delhi, India.

出版信息

Sultan Qaboos Univ Med J. 2017 May;17(2):e229-e233. doi: 10.18295/squmj.2016.17.02.017. Epub 2017 Jun 20.

Abstract

The monodermal teratoma is a rare ovarian tumour; however, presenting with pseudo-Meigs' syndrome and raised cancer antigen (CA)-125 levels is even rarer. In elderly patients, this presentation can potentially lead to a misdiagnosis of a malignant ovarian carcinoma, resulting in unnecessary extensive surgery. We report a 55-year-old female who presented to the Lok Nayak Jai Prakash Narayan Hospital, New Delhi, India, in 2016 with progressive abdominal discomfort, fatigue and abdominal distention. Clinical and radiological features were indicative of a malignant ovarian tumour and . Serum CA-125 levels were elevated at 258 U/mL. A left-sided salpingo-oophorectomy was performed, after which the serum CA-125 levels normalised. There was no evidence of recurrence at a six-month follow-up. A frozen section procedure confirmed the diagnosis of a . This rare condition should be considered as a differential diagnosis in patients presenting with ovarian masses, and raised CA-125 levels.

摘要

单胚层畸胎瘤是一种罕见的卵巢肿瘤;然而,伴有假性梅格斯综合征和癌抗原(CA)-125水平升高的情况更为罕见。在老年患者中,这种表现可能会导致误诊为恶性卵巢癌,从而导致不必要的广泛手术。我们报告一例55岁女性,2016年因进行性腹部不适、乏力和腹胀就诊于印度新德里的洛克·纳亚克·贾伊·普拉卡什·纳拉扬医院。临床和放射学特征提示为恶性卵巢肿瘤,血清CA-125水平升高至258 U/mL。行左侧输卵管卵巢切除术,术后血清CA-125水平恢复正常。六个月随访时无复发迹象。冰冻切片检查确诊为[此处原文缺失具体诊断内容]。对于出现卵巢肿块且CA-125水平升高的患者,应将这种罕见情况视为鉴别诊断之一。

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