膀胱的光声成像：一项初步研究。

Photoacoustic imaging of the bladder: a pilot study.

机构信息

Department of Radiology, Stanford University Medical Center, 300 Pasteur Dr, Stanford, CA 94305, USA.

出版信息

J Ultrasound Med. 2013 Jul;32(7):1245-50. doi: 10.7863/ultra.32.7.1245.

DOI:10.7863/ultra.32.7.1245

Abstract

Photoacoustic imaging is a promising new technology that combines tissue optical characteristics with ultrasound transmission and can potentially visualize tumor depth in bladder cancer. We imaged simulated tumors in 5 fresh porcine bladders with conventional pulse-echo sonography and photoacoustic imaging. Isoechoic biomaterials of different optical qualities were used. In all 5 of the bladder specimens, photoacoustic imaging showed injected biomaterials, containing varying degrees of pigment, better than control pulse-echo sonography. Photoacoustic imaging may be complementary to diagnostic information obtained by cystoscopy and urine cytologic analysis and could potentially obviate the need for biopsy in some tumors before definitive treatment.

摘要

光声成像是一种很有前途的新技术，它将组织光学特性与超声传输相结合，有可能实现膀胱癌肿瘤深度的可视化。我们使用传统的脉冲回波超声和光声成像对 5 个新鲜的猪膀胱模拟肿瘤进行了成像。使用了不同光学质量的等回声生物材料。在所有 5 个膀胱标本中，光声成像显示，含有不同程度色素的注射生物材料比对照脉冲回波超声显示得更好。光声成像是对膀胱镜检查和尿液细胞学分析获得的诊断信息的补充，有可能在某些肿瘤进行明确治疗之前，免除活检的需要。