Yuan Xueli, Zhuo Zhipeng, Wang Jun, Liu Xiaoli, Lü Meixia, Xu Jian
Department of Epidemiology and Heath Statistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Wei Sheng Yan Jiu. 2013 May;42(3):360-3, 368.
To study the relationship between the body mass index (BMI), waist circumference (WC) and lipids levels, dyslipidemia among adults.
Totally 12 communities from 8 districts were sampled through stratified randomized sampling, 75 households from each community were sampled by random sampling for questionnaire survey, physical examination and laboratory tests.
Within different BMI categories, the triglyceride (TG) in higher BMI group were higher than in lower BMI group, and the high density lipoprotein-c (HDL-c) in higher BMI group were lower than in higher BMI group; Within different WC categories, the TG, total cholesterol (TC), low density lipoprotein-c (LDL-c) in higher WC group were higher than in lower WC group. With the increase of BMI/WC, the levels of TG, TC and LDL-c showed a rising trend (P<0.05), HDL-c showed a falling trend (P<0.05). With the increase of BMI, the odds ratios (ORs) of high TG, high TC, low HDL-c, high LDL-c and dyslipidemia showed a rising trend (P<0.05), and with the increase of WC, the ORs of high TG, high TC, high LDL-c and dyslipidemia showed a rising trend (P<0.05). There were positive partial correlations between BMI/WC and TG, TC, HDL-c, LDL-c. HDL-c had a higher correlation with BMI (P<0.05), TC had a higher correlation with WC (P<0.05).
BMI and WC were independently associated with blood lipids levels, and high BMI and WC were the risk factors for dyslipidemia.
研究成年人身体质量指数(BMI)、腰围(WC)与血脂水平、血脂异常之间的关系。
通过分层随机抽样从8个区的12个社区中抽取样本,每个社区随机抽取75户进行问卷调查、体格检查和实验室检测。
在不同BMI类别中,较高BMI组的甘油三酯(TG)高于较低BMI组,较高BMI组的高密度脂蛋白胆固醇(HDL-c)低于较低BMI组;在不同WC类别中,较高WC组的TG、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-c)高于较低WC组。随着BMI/WC的增加,TG、TC和LDL-c水平呈上升趋势(P<0.05),HDL-c呈下降趋势(P<0.05)。随着BMI的增加,高TG、高TC、低HDL-c、高LDL-c和血脂异常的比值比(OR)呈上升趋势(P<0.05),随着WC的增加,高TG、高TC、高LDL-c和血脂异常的OR呈上升趋势(P<0.05)。BMI/WC与TG、TC、HDL-c、LDL-c之间存在正偏相关。HDL-c与BMI的相关性较高(P<0.05),TC与WC的相关性较高(P<0.05)。
BMI和WC与血脂水平独立相关,高BMI和WC是血脂异常的危险因素。