Sagara K
Department of Orthopaedic Surgery, Nagasaki University School of Medicine, Japan.
Nihon Seikeigeka Gakkai Zasshi. 1990 Apr;64(4):240-8.
The site of interrupted blood flow in the necrotic femoral heads of growing spontaneously hypertensive rats (SHR) and the state of the circulation during the reparative process were investigated by microangiography. The microangiographic findings of the femoral epiphysis were classified into the following four types: 1) uniform distribution of radiopacity; 2) absence of radiopacity in the medial portion; 3) complete absence of radiopacity; and 4) intercourse of blood vessels between the epiphysis and the metaphysis. These four types corresponded closely to the degree of the reparative process after necrosis and the retardation of ossification. The absence of blood vessels indicated the absence of reparative reaction or non-occurrence of ossification. These findings suggest that necrosis of the femoral head in SHR occurs as a result of interrupted blood flow outside the epiphyseal nucleus.
通过微血管造影术研究了自发性高血压大鼠（SHR）生长过程中坏死股骨头内血流中断的部位以及修复过程中的循环状态。股骨骨骺的微血管造影结果分为以下四种类型：1）不透射线均匀分布；2）内侧部分无不透射线；3）完全无不透射线；4）骨骺与干骺端之间血管相通。这四种类型与坏死后修复过程的程度和骨化延迟密切相关。血管缺失表明没有修复反应或未发生骨化。这些发现提示，SHR股骨头坏死是骨骺核外血流中断所致。
