Department of Gastroenterology and Hepatology, Beaumont Hospital, Dublin, Ireland.
Dig Endosc. 2013 Jul;25(4):392-6. doi: 10.1111/j.1443-1661.2012.01410.x. Epub 2012 Dec 17.
Gastric antral vascular ectasia (GAVE) or 'watermelon stomach' is a rare and often misdiagnosed cause of occult upper gastrointestinal bleeding. Treatment includes conservative measures such as transfusion and endoscopic therapy. A recent report suggests that endoscopic band ligation (EBL) offers an effective alternative treatment. The aim of the present study is to demonstrate our experiences with this novel technique, and to compare argon plasma coagulation (APC) with EBL in terms of safety and efficacy.
A retrospective analysis of all endoscopies with a diagnosis of GAVE was carried out between 2004 and 2010. Case records were examined for information pertaining to the number of procedures carried out, mean blood transfusions, mean hemoglobin, and complications.
A total of 23 cases of GAVE were treated. The mean age was 73.9 (55-89) years. Female to male ratio was 17:6 and mean follow up was 26 months. Eight patients were treated with EBL with a mean number of treatments of 2.5 (1-5). This resulted in a statistically significant improvement in the endoscopic appearance and a trend towards fewer transfusions. Of the eight patients treated with EBL, six (75%) patients had previously failed APC treatment despite having a mean of 4.7 sessions. Band ligation was not associated with any short- or medium-term complications. The 15 patients who had APC alone had a mean of four (1-11) treatments. Only seven (46.7%) of these patients had any endoscopic improvement with a mean of four sessions.
EBL represents a safe and effective treatment for GAVE.
胃底腺血管扩张症(GAVE)或“西瓜胃”是一种罕见且常被误诊的隐匿性上消化道出血原因。治疗包括输血和内镜治疗等保守措施。最近的一份报告表明,内镜套扎(EBL)提供了一种有效的替代治疗方法。本研究旨在展示我们使用这种新技术的经验,并比较氩等离子凝固(APC)与 EBL 在安全性和疗效方面的差异。
对 2004 年至 2010 年间所有诊断为 GAVE 的内镜检查进行回顾性分析。检查病历以获取有关手术次数、平均输血、平均血红蛋白和并发症的信息。
共治疗了 23 例 GAVE 患者。平均年龄为 73.9 岁(55-89 岁)。男女比例为 17:6,平均随访时间为 26 个月。8 例患者接受 EBL 治疗,平均治疗次数为 2.5 次(1-5 次)。这导致内镜表现明显改善,且输血次数减少。在接受 EBL 治疗的 8 例患者中,有 6 例(75%)尽管接受了平均 4.7 次 APC 治疗,但仍未成功。套扎治疗无短期或中期并发症。单独接受 APC 治疗的 15 例患者平均接受了 4 次(1-11 次)治疗。只有 7 例(46.7%)患者内镜有任何改善,平均接受了 4 次治疗。
EBL 是 GAVE 的一种安全有效的治疗方法。